Anti-Adenovirus Type 5 E1A antibody [SPM230], prediluted (ab17803)

Overview

  • Product nameAnti-Adenovirus Type 5 E1A antibody [SPM230], predilutedSee all Adenovirus Type 5 E1A primary antibodies ...
  • Description
    Mouse monoclonal [SPM230] to Adenovirus Type 5 E1A, prediluted
  • Tested applicationsIHC-Pmore details
  • Species reactivity
    Adenovirus
  • Immunogen

    Adenovirus

  • Positive control
    • 293 cells or adenovirus infected tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab17803 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notes
    IHC-P: Working dilution: Ready-to-use for 30 min at RT
    Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.
    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceThe early region (E1A) of the adenovirus genome plays a central role in cellular transformation and regulation of gene expression. The E1A region encodes a series of related proteins (35-46kDa) with multifuctional capabilities and form a specific complex with the retinoblastoma tumor suppressor gene product (Rb protein). The E1A and E1B regions together comprise the transforming region of adenovirus. While expression of E1A alone is sufficient to immortalize primary cells, complete transformation requires the additional expression of the E1B region. Several conserved regions of E1A are similar to portions of other viral oncoproteins like the HPV-16 and HPV-18 E7 and SV40 large T antigen.
    • Alternative names
      • Hadv 5 E1A antibody
      • HAdv5 E1A antibody

    References for Anti-Adenovirus Type 5 E1A antibody [SPM230], prediluted (ab17803)

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