Anti-Adenovirus Type 5 E1A antibody [SPM230], prediluted (ab17803)
- Product nameAnti-Adenovirus Type 5 E1A antibody [SPM230], predilutedSee all Adenovirus Type 5 E1A primary antibodies ...
- DescriptionMouse monoclonal [SPM230] to Adenovirus Type 5 E1A, prediluted
- Tested applicationsIHC-P more details
- Species reactivityAdenovirus
- Positive control293 cells or adenovirus infected tissues.
- Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C (add glycerol to a final volume of 50% for extra stability). Avoid repeated freeze / thaw cycles.
- Concentration information loading...
- Clonality Monoclonal
- Clone numberSPM230
- Light chain typekappa
- Research Areas
Our Abpromise guarantee covers the use of ab17803 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IHC-P: Working dilution: Ready-to-use for 30 min at RT
Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
- RelevanceThe early region (E1A) of the adenovirus genome plays a central role in cellular transformation and regulation of gene expression. The E1A region encodes a series of related proteins (35-46kDa) with multifuctional capabilities and form a specific complex with the retinoblastoma tumor suppressor gene product (Rb protein). The E1A and E1B regions together comprise the transforming region of adenovirus. While expression of E1A alone is sufficient to immortalize primary cells, complete transformation requires the additional expression of the E1B region. Several conserved regions of E1A are similar to portions of other viral oncoproteins like the HPV-16 and HPV-18 E7 and SV40 large T antigen.
- Hadv 5 E1A antibodyHAdv5 E1A antibody
References for Anti-Adenovirus Type 5 E1A antibody [SPM230], prediluted (ab17803)
This product has been referenced in:
- Nelson DA et al. Hypoxia and defective apoptosis drive genomic instability and tumorigenesis. Genes Dev 18:2095-107 (2004). Read more (PubMed: 15314031) »