Overview

  • Product nameAnti-Adiponectin Receptor 2 antibody
    See all Adiponectin Receptor 2 primary antibodies
  • Description
    Rabbit polyclonal to Adiponectin Receptor 2
  • SpecificityRecognizes mouse AdipoR2.
  • Tested applicationsIPmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Rat, Chicken, Human
  • Immunogen

    Synthetic peptide: NEPAKHRLGC TRTPEPDIRL RKGHQLDDTR GSNND, corresponding to amino acids 2-36 of Mouse Adiponectin Receptor 2

Applications

Our Abpromise guarantee covers the use of ab40446 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP 1/50.

Target

  • FunctionReceptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some intermediate-affinity receptor activity for both globular and full-length adiponectin.
  • Tissue specificityHighly expressed in skeletal muscle, liver and placenta. Weakly expressed in brain, heart, colon, spleen, kidney, thymus, small intestine, peripheral blood leukocytes and lung.
  • Sequence similaritiesBelongs to the ADIPOR family.
  • DomainThe N-terminus is known to be cytoplasmic while the C-terminus is known to be extracellular.
  • Cellular localizationMembrane. Localized to the cell membrane and intracellular organelles.
  • Information by UniProt
  • Database links
  • Alternative names
    • PAQR2 antibody
    • ACDCR2 antibody
    • Adiponectin receptor protein 2 antibody
    • Adipor2 antibody
    • ADR2_HUMAN antibody
    • Progestin and adipoQ receptor family member II antibody
    see all

References for Anti-Adiponectin Receptor 2 antibody (ab40446)

This product has been referenced in:
  • Ogunwobi OO & Beales IL Globular adiponectin, acting via adiponectin receptor-1, inhibits leptin-stimulated oesophageal adenocarcinoma cell proliferation. Mol Cell Endocrinol 285:43-50 (2008). Read more (PubMed: 18313838) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"