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Product Name 

Agmatine antibody

 

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Product type 

Primary antibodies

Description 

Chicken polyclonal to Agmatine

Immunogen 

Agmatine cross-linked to purifed fraction V bovine serum albumin with glutaraldehyde.

Species Reactivity 

Not applicable.

Specificity 

Fixed tissue cross-reactivity tested with known targets at recommended dilution.
No measurable glutaraldehyde-fixed tissue cross-reactivity (<1:1000) against L-alanine, gamma-aminobutyrate, L-citrulline, L-cysteine, D/L-glutamate, D/L-arginine, D/L-glutamine, glutathione, glycine, L-lysine, L-ornithine, L-serine, taurine, L-threonine, L-tryptophan, L-tyrosine.

Tested applications 
(see key)

ICC


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Application notes 
(see key)

Recommended dilutions
ICC: 1/100. Excitation mapping by LM immunocytochemistry. True dilution at user dilution: 1/2000. Optimal fixation: 0.1-2.5% glutaraldehyde,1% formaldehyde using HPI (High Performance Immunocytochemistry). Minimum glutaraldehyde: 0.1% using HPI.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Research areas 

Signal Transduction >> Metabolism >> Drug metabolism
Neuroscience >> Neurotransmitter >> Biogenic Amines >> Other Amines
Neuroscience >> Sensory System >> somatosensory system >> Nociception
Signal Transduction >> Metabolism >> Amino Acids

Relevance 

Agmatine, a product of arginine metabolism is an endogenous amine acting at imidazoline receptors with a putative role in nociception at the spinal level. Agmatine potentiates morphine analgesia and blocks symptoms of naloxone-precipitated morphine withdrawal in rats.

 

Alternative names Agmatine antibody (ab62667)

Raised in 

Chicken

Clonality 

Polyclonal

Isotype 

IgY

Purity 

IgY fraction

Storage buffer 

Preservative: 0.05% Thimerosal (merthiolate)
Constituents: 100mM Phosphate buffer, 1% sterilized goat serum

Material safety datasheet (MSDS) for this product:
Thimerosal MSDS

Purification notes 

IgYs were separated from other yolk proteins by serial PEG6000 extractions using a modification of the method of Polsonet al Immunological Investigations. 1985, 14, 323-327.

Form 

Liquid

Concentration 

3.000 mg/ml

Storage instructions 

Store at +4°C. Do not freeze.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Agmatine antibody is on this datasheet. But please do contact us if you would like any reassurance!


 

Search PubMed (MEDLINE) for references to Agmatine

 

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Agmatine antibody - related products:

Products for Immunocytochemistry

Subcellular Markers

 

Compatible IgY Secondaries for Agmatine antibody

ab6749

  

Rabbit polyclonal to Chicken IgY - H&L (FITC)

ab6752

  

Rabbit polyclonal to Chicken IgY - H&L (Biotin)

ab6753

  

Rabbit polyclonal to Chicken IgY - H&L (HRP)

ab6877

  

Goat polyclonal to Chicken IgY - H&L (HRP)

ab7117

  

Goat polyclonal to Chicken IgY - H&L - Pre-Adsorbed (Biotin)

 

Other Agmatine Antibodies

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