Ago2 / eIF2C2 peptide (ab24177)

Product Name 

Ago2 / eIF2C2 peptide

Product type 

Proteins and Peptides

Peptide 

Synthetic peptide derived from within residues 550 - 650 of Fruit fly (Drosophila melanogaster) Ago2.

This peptide was used as an immunogen for ab5072 - Ago2 antibody.

Application notes 
(see key)

Recommended dilutions
This peptide can be used with studies using ab5072.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Research areas 

Chromatin and Nuclear Signaling >> Nuclear Signaling Pathways >> Nuclear Receptors >> Nuclear Pore Complex
Chromatin and Nuclear Signaling >> RNAi >> Eukaryotic Initiation factors (eIF's)
Chromatin and Nuclear Signaling >> RNAi >> Argonaute and Piwi
Chromatin and Nuclear Signaling >> DNA / RNA >> RNA Processing >> RNAi

Relevance 

Ago2 is essential for RNA interference (RNAi), where double-stranded RNA induces potent and specific gene silencing. RNAi is mediated by the RNA-induced silencing complex (RISC), a sequence-specific, multicomponent nuclease that destroys messenger RNAs homologous to the silencing trigger.

Storage buffer 

Preservative: None
Constituents: 0.001% Tween 20, 30mM HEPES, 2mM EDTA, 150mM Sodium chloride. pH 6.75

Form 

Liquid

Concentration 

1.000 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

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