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Products:Signal Transduction >> Metabolism >> Energy Metabolism
Overview
Product name
Anti-Aldolase antibody
See all Aldolase products (11) ...
Description
Mouse monoclonal to Aldolase
Tested applications
WB, ICC/IFmore details
Cross reactivity
Reacts with
Human
Immunogen
Recombinant full length protein, corresponding to amino acids 1-365 of Human Aldolase
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Isotype
IgG1
Light chain type
kappa
Research areas
Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Metabolism of carbohydrates
Signal Transduction >> Metabolism >> Energy Metabolism
Applications
Show applications key
Our Abpromise guarantee covers the use of ab54770 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use a concentration of 1 - 5 µg/ml.Predicted molecular weight: 39 kDa.
ICC/IF: Use a concentration of 10 µg/ml
Target
Relevance
This gene product, Aldolase A (fructose bisphosphate aldolase) is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3 phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing of this gene results in multiple transcript variants which encode the same protein.
Cellular localization
Cytoplasmic
Alternative names
- ALDA antibody
- ALDOA antibody
- Aldolase A antibody
see all
Database links
- Entrez Gene: 226 Human
- Omim: 103850 Human
- SwissProt: P04075 Human
- SwissProt: Q6FI10 Human
- Unigene: 513490 Human
Anti-Aldolase antibody images:
Western blot - Aldolase antibody (ab54770)
Aldolase antibody (ab54770) at 1ug/lane + A-431 cell lysate at 25ug/lane.
Immunocytochemistry/ Immunofluorescence - Aldolase antibody (ab54770)
ab54770 at 10 ug/ml staining Aldolase in human Hela cells by Immunocytochemistry / Immunofluorescence.
References for Anti-Aldolase antibody (ab54770)
This product has been referenced in:
- Sørensen BSet al. Proteins upregulated by mild and severe hypoxia in squamous cell carcinomas in vitro identified by proteomics. Radiother Oncol 92:443-9 (2009). WB; Human.Read more (PubMed: 19541378) »
See 1 publication for this product
Publishing research using ab54770? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"