Anti-Alpha 1 Acid Glycoprotein antibody (ab52691)

Overview

• Product nameAnti-Alpha 1 Acid Glycoprotein antibodySee all Alpha 1 Acid Glycoprotein primary antibodies ...
• Description
  Mouse polyclonal to Alpha 1 Acid Glycoprotein
• Tested applicationsWB more details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Synthetic peptide: ENGTISRYVG GQEHFAHLLI LRDTKTYMLA FDVNDEKNWG LSVYADKPET TKEQLGEFYE ALDCLRIPKS DVVYTDWKKD KCEPLEKQHE KERKQEEGES , corresponding to amino acids 102-202 of Human Alpha 1 Acid Glycoprotein

  Run BLAST with Run BLAST with

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Storage bufferPreservative: None
  Constituents: 50% Glycerol, Whole serum
• PurityWhole antiserum
• Primary antibody notes This antibody was raised by a genetic immunization technique. Genetic immunization can be used to generate antibodies by directly delivering antigen-coding DNA into the animal, rather than injecting a protein or peptide (Tang et al. PubMed: 1545867; Chambers and Johnston PubMed 12910245; Barry and Johnston PubMed: 9234514). The animal's cells produce the protein, which stimulates the animal's immune system to produce antibodies against that particular protein. A vector coding for a partial fusion protein was used for genetic immunisation of a mouse and the resulting serum was tested in Western blot against an E.coli lysate containing that partial fusion protein. Genetic immunization offers enormous advantages over the traditional protein-based immunization method. DNA is faster, cheaper and easier to produce and can be produced by standard techniques readily amenable to automation. Furthermore, the antibodies generated by genetic immunization are usually of superior quality with regard to specificity, affinity and recognizing the native protein.
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Cardiovascular
  • Blood
  • Acute Phase Reactants

  • Cardiovascular
  • Blood
  • Serum Proteins

  • Immunology
  • Secreted Molecules
  • Other secreted molecules

  • Immunology
  • Innate Immunity
  • Macrophage / Inflamm.

Applications

Target

• FunctionAppears to function in modulating the activity of the immune system during the acute-phase reaction.
• Tissue specificityExpressed by the liver and secreted in plasma.
• Sequence similaritiesBelongs to the calycin superfamily. Lipocalin family.
• Cellular localizationSecreted.

Target information above from: UniProt accession P02763 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 5004 Human
  • Omim: 138600 Human
  • SwissProt: P02763 Human
  • Unigene: 522356 Human

• Alternative names
  A1AG1_HUMAN antibodyAGP 1 antibodyAGP A antibody

  AGP antibodyagp1 antibodyagpa antibodyAlpha 1 acid glycoprotein antibodyAlpha 1 agp antibodyAlpha-1-acid glycoprotein 1 antibodyGlycoprotein alpha acid of serum antibodyOMD 1 antibodyomd1 antibodyorm antibodyORM1 antibodyOrosomucoid 1 antibodyOrosomucoid-1 antibodyOrosomucoid1 antibody

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Anti-Alpha 1 Acid Glycoprotein antibody images

• 

  Western blot - Alpha 1 Acid Glycoprotein antibody (ab52691)
  All lanes : Anti-Alpha 1 Acid Glycoprotein antibody (ab52691) at 1/1000 dilution
  
  Lane 1 : Left: The negative control lane of ~20ug of a total protein extract from E coli with ~50ng to 100 ng of a fusion protein of an irrelevant antigen.
  Lane 2 : Right: test lane of ~20ug of a total protein extract from E coli with ~50ng to 500ng of the antigen (antigen fusion protein).
  
  Secondary
  Rabbit anti-mouse IgG + IgM, (H+L) horseradish peroxidase conjugated at 1/5000 dilution
  
  Predicted band size : 24 kDa