Anti-Alpha 2 Antiplasmin antibody (ab96626)

Overview

• Product nameAnti-Alpha 2 Antiplasmin antibodySee all Alpha 2 Antiplasmin primary antibodies ...
• Description
  Rabbit polyclonal to Alpha 2 Antiplasmin
• Tested applicationsWB more details
• Species reactivity
  Reacts with: Human
  Predicted to work with: Rabbit
• Immunogen

  Recombinant protein fragment corresponding to a region within amino acids 188 - 423 of Human Alpha 2 Antiplasmin (NP_000925).

• Positive control293T, A431, H1299, HeLa, HepG2, MOLT4 and Raji cell lysates

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: 0.01% Thimerosal (merthiolate)
  Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
• Concentration information loading...
• PurityImmunogen affinity purified
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Cardiovascular
  • Blood
  • Fibrinolysis / Thrombolysis

  • Cardiovascular
  • Blood
  • Coagulation
  • Regulatory

  • Cell Biology
  • Proteolysis / Ubiquitin
  • Protease inhibitors
  • Serine protease inhibitors
  • SERPINs

  • Cell Biology
  • Proteolysis / Ubiquitin
  • Protease inhibitors
  • Other protease inhibitors

Applications

Target

• FunctionSerine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin.
• Tissue specificityExpressed by the liver and secreted in plasma.
• Involvement in diseaseDefects in SERPINF2 are the cause of alpha-2-plasmin inhibitor deficiency (APLID) [MIM:262850]. APLID is an autosomal recessive disorder resulting in severe hemorrhagic diathesis.
• Sequence similaritiesBelongs to the serpin family.
• Cellular localizationSecreted.

Target information above from: UniProt accession P08697 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 5345 Human
  • Entrez Gene: 100009515 Rabbit
  • Omim: 262850 Human
  • SwissProt: P08697 Human
  • Unigene: 159509 Human

• Alternative names
  A2AP antibodyA2AP_HUMAN antibodyAAP antibody

  Alpha 2 antiplasmin antibodyAlpha 2 antiplasmin pigment epithelium derived factor antibodyAlpha 2 AP antibodyALPHA 2 PI antibodyAlpha 2 plasmin inhibitor antibodyAlpha 2 plasmin inhibitor deficiency antibodyAlpha-2-antiplasmin antibodyAlpha-2-AP antibodyAlpha-2-PI antibodyAlpha-2-plasmin inhibitor antibodyAntiplasmin deficiency antibodyAPI antibodyPlasmin inhibitor deficiency antibodyPLI antibodySerine (or cysteine) peptidase inhibitor, clade F, member 2 antibodySerine (Or cysteine) peptidase inhibitor, clade F, member 2, isoform CRA_c antibodySerine (or cysteine) proteinase inhibitor, clade F (alpha 2 antiplasmin pigment epithelium derived factor) member 2 antibodySerine (Or cysteine) proteinase inhibitor, clade F, member 2 antibodySerine or cysteine peptidase inhibitor clade F member 2 antibodySerpin F2 antibodySerpin peptidase inhibitor clade F antibodySerpin peptidase inhibitor, clade F (alpha 2 antiplasmin pigment epithelium derived factor) member 2 antibodySERPINF2 antibody

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Anti-Alpha 2 Antiplasmin antibody images

• 

  Western blot - Alpha 2 Antiplasmin antibody (ab96626)
  Anti-Alpha 2 Antiplasmin antibody (ab96626) at 1/1000 dilution + HeLa whole cell lysate at 30 µg
  
  Predicted band size : 55 kDa