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Product Name 

Alpha 2 HS Glycoprotein antibody

 

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Product type 

Primary antibodies

Description 

Sheep polyclonal to Alpha 2 HS Glycoprotein

Immunogen 

Full length native protein (purified): Human alpha-2-HS-Glycoprotein, purified from human serum.

Reacts with 

Hu

Does not react with 
(species key)

Ms, Rat, Cat, Chk, Cow, Dog, Goat, Gpig, Hrs, Pig, Rb

Tested applications 
(see key)

DID, Ie, RID


Abreviews 

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Application notes 
(see key)

Recommended dilutions
DID: 5 microl antiserum/cm2 in gel vs 5 microl serum, NT - 1:10.
Ie: 100 microl antiserum vs 5 microl serum.
RID: 10 microl antiserum vs 2 microl serum.

Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Cellular localization 

Secreted

Research areas 

Neuroscience >> Neurology process >> Neurogenesis
Cardiovascular >> Blood >> Serum Proteins

Relevance 

Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has therefore been postulated that it participates in the development of the tissues. However, its exact significance is still obscure. It promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. It shows affinity for calcium and barium ions.

 

Alpha 2 HS Glycoprotein antibody (ab21201)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

197    (Human)

Omim

    

138680    (Human)

SwissProt

    

P02765    (Human)

Raised in 

Sheep

Clonality 

Polyclonal

Isotype 

IgG

Storage buffer 

Preservative: 0.1% Sodium Azide, 0.1% E-Amino-n-Caproic Acid, 0.01% Benzamidine, and 1mM EDTA
Constituents: Glycine buffered saline. pH 7.4

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Purification notes 

Delipidated and if necessary absorbed to monospecificity by use of solid-phase adsorbants. Following adsorption, an immunoglobulin fraction is produced by ion-exchange chromatography. Product is 0.2 microm filtered.

Form 

Liquid

Concentration 

19.000 mg/ml

Storage instructions 

Store at +4°C.

 

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Other Alpha 2 HS Glycoprotein Antibodies

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