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Product Name
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Alpha 2 HS Glycoprotein antibody
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See all Alpha 2 HS Glycoprotein antibodies (6)...
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Product type
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Primary antibodies
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Description
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Sheep polyclonal to Alpha 2 HS Glycoprotein
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Immunogen
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Full length native protein (purified): Human alpha-2-HS-Glycoprotein, purified from human serum.
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Reacts with
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Hu
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Does not react with
(species key)
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Ms, Rat, Cat, Chk, Cow, Dog, Goat, Gpig, Hrs, Pig, Rb
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Tested applications
(see key)
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DID, Ie, RID
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Abreviews
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Application notes
(see key)
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Recommended dilutions
DID: 5 microl antiserum/cm2 in gel vs 5 microl serum, NT - 1:10.
Ie: 100 microl antiserum vs 5 microl serum.
RID: 10 microl antiserum vs 2 microl serum.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Secreted
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Research areas
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Neuroscience >> Neurology process >> Neurogenesis
Cardiovascular >> Blood >> Serum Proteins
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Relevance
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Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has therefore been postulated that it participates in the development of the tissues. However, its exact significance is still obscure. It promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. It shows affinity for calcium and barium ions.
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Alpha 2 HS Glycoprotein antibody (ab21201) |
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Sheep
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Clonality
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Polyclonal
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Isotype
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IgG
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Storage buffer
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Preservative: 0.1% Sodium Azide, 0.1% E-Amino-n-Caproic Acid, 0.01% Benzamidine, and 1mM EDTA
Constituents: Glycine buffered saline. pH 7.4 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Purification notes
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Delipidated and if necessary absorbed to monospecificity by use of solid-phase adsorbants. Following adsorption, an immunoglobulin fraction is produced by ion-exchange chromatography. Product is 0.2 microm filtered.
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Form
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Liquid
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Concentration
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19.000 mg/ml
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Storage instructions
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Store at +4°C.
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Search PubMed (MEDLINE) for references to Alpha 2 HS Glycoprotein
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