Alpha 2 HS Glycoprotein antibody (ab35047)

Product Name 

Alpha 2 HS Glycoprotein antibody

Product type 

Primary antibodies

Description 

Rabbit polyclonal to Alpha 2 HS Glycoprotein

Immunogen 

Full length native protein (Human)

Reacts with 
(species key)

Hu

Tested applications 
(see key)

ELISA, WB

Abreviews 

Customer reviews (see key)

Read about Abreviews

Application notes 
(see key)

Recommended dilutions
ELISA: 1/4000 (50%B).
ELISA: 1/200K (EPT).
WB: 1/100. Detects a band of approximately 56 kDa, a duplet+ 36 - 42 kDa band and a diffuse band of 27/29 kDa. MW from peptide sequence is 44 kD but AHSD is glycosylated.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Positive control 
(see definition)

Normal human serum.

Cellular localization 

Secreted

Research areas 

Neuroscience >> Neurology process >> Neurogenesis
Signal Transduction >> Cytoskeleton / ECM >> Extracellular Matrix >> Structures >> Bone
Neuroscience >> Neurology process >> Neural Signal Transduction
Neuroscience >> Cell Adhesion Proteins >> ECM Proteins
Cardiovascular >> Blood >> Serum Proteins

Relevance 

Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has therefore been postulated that it participates in the development of the tissues. However, its exact significance is still obscure. It promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. It shows affinity for calcium and barium ions.

Database links 

Raised in 

Rabbit

Clonality 

Polyclonal

Isotype 

IgG

Purity 

IgG fraction

Storage buffer 

Preservative: 0.1% Sodium Azide
Constituents: PBS, pH 7.2

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Purification notes 

Ammonium Sulphate fractionation.

Form 

Liquid

Concentration 

Batch dependent within range: 2.90 - 5.00 mg/ml

Concentration of lot no.     is  

Concentration not available for this lot.

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Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

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