Overview

  • Product name
    Anti-Alpha B Crystallin antibody
    See all Alpha B Crystallin primary antibodies
  • Description
    Goat polyclonal to Alpha B Crystallin
  • Tested applications
    Suitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
    Predicted to work with: Sheep, Rabbit, Chicken, Guinea pig, Hamster, Cow, Pig, Cynomolgus monkey, Orangutan
  • Immunogen

    Synthetic peptide:

    RLEKDRFSVNLD

    , from the internal region of human alpha B Crystallin

  • Positive control
    • WB: Mouse and rat eye lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab65940 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
WB
  • Application notes
    WB: Use at a concentration of 0.01 - 0.03 µg/ml. Detects a band of approximately 18-19 kDa (predicted molecular weight: 20 kDa).
    Peptide ELISA: antibody detection limit dilution 1:128,000.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      May contribute to the transparency and refractive index of the lens.
    • Tissue specificity
      Lens as well as other tissues.
    • Involvement in disease
      Defects in CRYAB are the cause of myofibrillar alpha-B crystallin-related (MFM-CRYAB) [MIM:608810]. A neuromuscular disorder that results in weakness of the proximal and distal limb muscles, weakness of the neck, velopharynx and trunk muscles, hypetrophic cardiomyopathy, and cataract in a subset of patients.
    • Sequence similarities
      Belongs to the small heat shock protein (HSP20) family.
    • Cellular localization
      Cytoplasm. Nucleus. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
    • Information by UniProt
    • Database links
    • Alternative names
      • AACRYA antibody
      • Alpha B crystallin antibody
      • Alpha crystallin B chain antibody
      • Alpha(B)-crystallin antibody
      • Alpha-crystallin B chain antibody
      • CRYA2 antibody
      • Cryab antibody
      • CRYAB_HUMAN antibody
      • Crystallin alpha B antibody
      • Crystallin alpha polypeptide 2 antibody
      • CTPP2 antibody
      • Heat shock 20 kD like protein antibody
      • Heat shock protein beta 5 antibody
      • Heat shock protein beta-5 antibody
      • HspB5 antibody
      • Renal carcinoma antigen NY REN 27 antibody
      • Renal carcinoma antigen NY-REN-27 antibody
      • Rosenthal fiber component antibody
      see all

    Images

    • All lanes : Anti-Alpha B Crystallin antibody (ab65940) at 0.05 µg/ml

      Lane 1 : Mouse eye lysate
      Lane 2 : Rat eye lysate

      Lysates/proteins at 35 µg per lane.


      Predicted band size : 20 kDa

    References

    ab65940 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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