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Alpha B Crystallin protein (Mouse) (ab94437)

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Overview

  • Product nameAlpha B Crystallin protein (Mouse)See all Alpha B Crystallin proteins and peptides ...
  • Protein descriptionRecombinant full length protein, corresponding to amino acids 1-175 of Mouse Alpha B Crystallin. Predicted molecular weight: 20 kDa; Uniprot ID P23927.
  • Expression hostE. coli

    • Properties

  • Purity> 95 % by SDS-PAGE
  • Purification notesPurified by proprietary chromatographic techniques. <95% as determined by SDS-PAGE and RP-HPLC.
  • FormLiquid
  • Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 10% Glycerol, 20mM Tris buffered saline, pH 8.0
  • Concentration information loading...
  • Additional notesFor long term storage, addition of a carrier protein (0.1% HSA or BSA) is recommended.
  • Sequence notesMDIAIHHPWI RRPFFPFHSP SRLFDQFFGE HLLESDLFST ATSLSPFYLR PPSFLRAPSW IDTGLSEMRL EKDRFSVNLD VKHFSPEELK VKVLGDVIEV HGKHEERQDE HGFISREFHR KYRIPADVDP LTITSSLSSD GVLTVNGPRK QVSGPERTIP ITREEKPAVA AAPKK
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab94437 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    SDS-PAGE
  • Application notesSDS-PAGE: Use at an assay dependent dilution.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Protein info

    • Alternative names
        AACRYAAlpha B crystallinAlpha crystallin B chain
        Alpha(B)-crystallinAlpha-crystallin B chainCRYA2CRYABCRYAB_HUMANCrystallin alpha BCrystallin alpha polypeptide 2CTPP2Heat shock 20 kD like proteinHeat shock protein beta 5Heat shock protein beta-5HSPB5Renal carcinoma antigen NY REN 27Renal carcinoma antigen NY-REN-27Rosenthal fiber component
      see all
  • FunctionMay contribute to the transparency and refractive index of the lens.
  • Tissue specificityLens as well as other tissues.
  • Involvement in diseaseDefects in CRYAB are the cause of myofibrillar alpha-B crystallin-related (MFM-CRYAB) [MIM:608810]. A neuromuscular disorder that results in weakness of the proximal and distal limb muscles, weakness of the neck, velopharynx and trunk muscles, hypetrophic cardiomyopathy, and cataract in a subset of patients.
  • Sequence similaritiesBelongs to the small heat shock protein (HSP20) family.
  • Cellular localizationCytoplasm. Nucleus. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.

    • Target information above from: UniProt accession P02511 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for Alpha B Crystallin protein (Mouse) (ab94437)

    ab94437 has not yet been referenced specifically in any publications.

    Publishing research using ab94437 ? Please let us know so that we can cite the reference in this datasheet

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