Overview
Product nameAlpha Thrombin protein (Active)See all Alpha Thrombin proteins and peptides ...
Protein descriptionFull length protein, corresponding to amino acids 328-622 of Human Alpha Thrombin; 295 amino acids, 34kDa. Swiss ID = P00734.
Expression hostNative
Properties
Purity> 95
% by SDS-PAGE
Biological activitySpecific Activity: <1% Thrombin activity.
Active site blocked by FPR- chloromethylketone.
FormLiquid
Storage instructionsShipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.This product is an active protein and may elicit a biological response in vivo, handle with caution.
Storage bufferPreservative: None
Constituents: 20mM HEPES, 150mM Sodium chloride, pH 7.4
Concentration information loading...
Research Areas
Applications
Our Abpromise guarantee covers the use of
ab81589
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|
Application
|
Notes |
| Functional Studies |
FuncS: Use at an assay dependent dilution. |
| SDS-PAGE |
SDS-PAGE: Use at an assay dependent dilution. |
Protein info
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Alternative names
Coagulation factor IICoagulation factor II (thrombin)F2
prothrombin B-chainPTserine protease
see all
RelevanceThrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.
Cellular localizationSecreted › extracellular space.
References for Alpha Thrombin protein (Active) (ab81589)
ab81589
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
