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Read our guarantee »Overview
Product name
Aminoguanidine hydrochloride
Description
NOS inhibitor
Biological description
Irreversible inhibitor of iNOS, displaying 26-fold selectivity over nNOS. In vitro and in vivo inhibitor of the formation of glycosylation end products associated with diabetes and aging.
Purity
> 98%
General notes
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Properties
Chemical name
Guanylhydrazine hydrochloride
Molecular Weight
110.55
Chemical structure
Molecular formula
CH6N4.HCl
CAS Number
1937-19-5
Solubility
Soluble in water to 100 mM
Storage instructions
Store at room temperature.
Research areas
Biochemicals >> Research Area >> Stroke >> Signaling >> Nitric Oxide >> NOS >> Inhibitors
Biochemicals >> Research Area >> Respiratory disease >> Signaling >> Nitric Oxide >> NOS >> Inhibitors
Biochemicals >> Research Area >> Pain & inflammation >> Signaling >> Nitric Oxide >> NOS >> Inhibitors
Biochemicals >> Research Area >> Obesity >> Signaling >> Nitric Oxide >> NOS >> Inhibitors
Biochemicals >> Research Area >> Hypertension >> Signaling >> Nitric Oxide >> NOS >> Inhibitors
Biochemicals >> Research Area >> Heart disease >> Signaling >> Nitric Oxide >> NOS >> Inhibitors
Biochemicals >> Research Area >> Diabetes >> Signaling >> Nitric Oxide >> NOS >> Inhibitors
Biochemicals >> Research Area >> Cancer >> Signaling >> Nitric Oxide >> NOS >> Inhibitors
Biochemicals >> Research Area >> Alzheimer's Disease >> Signaling >> Nitric Oxide >> NOS >> Inhibitors
Biochemicals >> Pharmacology >> Signaling >> Nitric Oxide >> NOS >> Inhibitors
Biochemicals >> Pharmacology >> Enzymes >> Synthetase & synthase >> Inhibitors
Biochemicals >> Chemical Type >> Biochemicals
Biochemicals >> Product Range >> Just Add Water
References for Aminoguanidine hydrochloride (ab120123)
This product has been referenced in:
- Nilsson BO Biological effects of aminoguanidine: an update. Inflamm Res 48:509-15 (1999).Read more (PubMed: 10563466) »
- Moore PK & Handy RL Selective inhibitors of neuronal nitric oxide synthase--is no NOS really good NOS for the nervous system? Trends Pharmacol Sci 18:204-11 (1997).Read more (PubMed: 9226999) »
See all 3 publications for this product
Publishing research using ab120123? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"