You have changed your country from  to  . Please be aware that this will change the currency in the purchasing process.
AbcamBiochemicals (Asc-480)

Amyloid β Peptide (25-35) (human) (ab120480)

Q&A (2)

Overview

  • Product nameAmyloid β Peptide (25-35) (human)
  • Description
    Highly toxic amyloid β protein fragment
  • Biological descriptionHighly toxic, synthetic peptide fragment of the amyloid β protein. Displays extremely rapid aggregation and enhanced neurotoxicity. Increases oxidative stress, causes neuronal damage and decreases spatial memory in rats.
  • Purity> 95%

    • Properties

  • Chemical nameGSNKGAIIGLM
  • Molecular Weight1060.27
  • Chemical structureChemical Structure
  • Molecular formulaC45H81N13O14S
  • CAS Number131602-53-4
  • Storage instructionsStore at -20°C (desiccating conditions).
  • Solubility overviewSoluble in water
  • Handling

    Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months.

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

  • Source

    Synthetic

  • Research Areas

    • References for Amyloid β Peptide (25-35) (human) (ab120480)

    This product has been referenced in:
    • Limón ID  et al. Amyloid-beta(25-35) impairs memory and increases NO in the temporal cortex of rats. Neurosci Res 63:129-37 (2009). Read more (PubMed: 19084561) »
    • Millucci L  et al. Rapid aggregation and assembly in aqueous solution of A beta (25-35) peptide. J Biosci 34:293-303 (2009). Read more (PubMed: 19550045) »
    • Hughes E  et al. Inhibition of toxicity in the beta-amyloid peptide fragment beta -(25-35) using N-methylated derivatives: a general strategy to prevent amyloid formation. J Biol Chem 275:25109-15 (2000). Read more (PubMed: 10825171) »

    See 0 Publications for this product

    Publishing research using ab120480 ? Please let us know so that we can cite the reference in this datasheet

    Product Wall

    Submit a Question for ab120480

    Displaying 1 - 2 of 2 results for Q&A

    10
    Votes: Highest First

    Hi:
    I am testing the cell viability(MTS)after adding amyloid on them with different doses.This is just the first step in my work to see the toxic effect of Amyloid on cells.But my questions are:
    1-Is amyloid solubles in pbs directly or distilled...

    Read More

    Thank you for your response.

    Unfortunately we don’t have any specific data for this compound. However,this product has been used in the paper attached. The materials and methods section describes how they used PBS to dissolve the compound ...

    Read More

    hi ,I am working with this product in 96 well plate and neuroblastoma cell line .I used it for more than 4 plates but the results was not good ,in other word the viabilty of cells wasnot related to the doses of amyloid.So may be I have a problem with the ...

    Read More

    Thank you providing the product code number and the order number in your previous e-mail. I am very sorry to hear that you are having problems with this antibody.

    Could you provide some further details of the protocol used? Are you using it in E...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"