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Angiotensin Converting Enzyme 1 peptide (Carboxyterminal end) (ab41280)

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Overview

Product name

Angiotensin Converting Enzyme 1 peptide (Carboxyterminal end)
See all Angiotensin Converting Enzyme 1 products (5) ...

Protein description

Synthetic peptide Angiotensin Converting Enzyme 1. (Note: the amino acid sequence is proprietary) This peptide was used as an immunogen for ab39172 - Angiotensin Converting Enzyme 1 antibody - Carboxyterminal end.

Properties

Purity

>95% by SDS-PAGE

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: None
Constituents: 0.001% Tween 20, 30mM HEPES, 2mM EDTA, 150mM Sodium chloride, pH 6.75

Concentration

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Applications

Show applications key

Our Abpromise guarantee covers the use of ab41280 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ELISA

     
  • WB

     

Application notes

ELISA: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. This peptide can be used with studies using ab39172. Dilution optimised using Chromogenic detection. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Protein info

Relevance

ACE converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilatator. ACE exists in two forms, a 170KD somatic form and a 90KD germinal form. The somatic form is expressed by endothelial cells (especially those of lung capillaries and arterioles), epithelial cells (especially in proximal renal tubules and small intestine), by some neuronal cells and variably by some macrophages and T lymphocytes. The germinal form is expressed by spermatozoa.

Cellular localization

Cell Membrane

References for Angiotensin Converting Enzyme 1 peptide (Carboxyterminal end) (ab41280)

ab41280 has not yet been referenced specifically in any publications.

Publishing research using ab41280? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"