Overview
Product nameAngiotensin Converting Enzyme 2 peptide (Catalytic domain)See all Angiotensin Converting Enzyme 2 proteins and peptides ...
Protein descriptionSynthetic peptide Angiotensin Converting Enzyme 2.
(Note: the amino acid sequence is proprietary)
This peptide was used as an immunogen for ab38888 - Angiotensin Converting Enzyme 2 antibody - Catalytic domain.
Properties
Purity> 95
% by SDS-PAGE
FormLiquid
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferPreservative: None
Constituents: 0.001% Tween 20, 30mM HEPES, 2mM EDTA, 150mM Sodium chloride, pH 6.75
Concentration information loading...
Research Areas
Applications
Our Abpromise guarantee covers the use of
ab41282
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Application
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Notes |
| ELISA |
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| WB |
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Application notesELISA: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. This peptide can be used with studies using ab38888. Dilution optimised using Chromogenic detection. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Protein info
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Alternative names
ACE 2ACE related carboxypeptidaseACE-related carboxypeptidase
ACE2ACE2_HUMANACEHAngiotensin converting enzyme 2Angiotensin converting enzyme homologAngiotensin converting enzyme like proteinAngiotensin I Converting Enzyme (peptidyl dipeptidase A) 2Angiotensin I converting enzyme 2Angiotensin-converting enzyme homologDKFZP434A014EC 3.4.17metalloprotease MPROT 15Metalloprotease MPROT15OTTHUMP00000022963Processed angiotensin-converting enzyme 2
see all
FunctionCarboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.
Tissue specificityExpressed in endothelial cells from small and large arteries, and in arterial smooth muscle cells. Expressed in lung alveolar epithelial cells, enterocytes of the small intestine, Leydig cells and Sertoli cells (at protein level). Expressed in heart, kidney, testis, and gastrointestinal system.
Sequence similaritiesBelongs to the peptidase M2 family.
Post-translational
modificationsN-glycosylation on Asn-90 may limit SARS infectivity.
Cellular localizationSecreted and Cell membrane.
References for Angiotensin Converting Enzyme 2 peptide (Catalytic domain) (ab41282)
ab41282
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
