Overview

  • Product name
  • Description
    Rabbit polyclonal to Annexin A1
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to N-terminus of human Annexin A1. The amino acid sequence is unavialable.

  • Positive control
    • Human placenta.

Properties

Applications

Our Abpromise guarantee covers the use of ab41830 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notes
    IHC-P: 1/25 for 30 min at RT. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity.
    • Sequence similarities
      Belongs to the annexin family.
      Contains 4 annexin repeats.
    • Domain
      A pair of annexin repeats may form one binding site for calcium and phospholipid.
    • Post-translational
      modifications
      Phosphorylated by protein kinase C, epidermal growth factor receptor/kinase and TRPM7. Phosphorylation results in loss of the inhibitory activity.
    • Cellular localization
      Nucleus. Cytoplasm. Cell projection > cilium. Basolateral cell membrane. Found in the cilium, nucleus and basolateral cell membrane of ciliated cells in the tracheal endothelium (By similarity). Found in the cytoplasm of type II pneumocytes and alveolar macrophages.
    • Information by UniProt
    • Database links
    • Alternative names
      • Annexin 1 antibody
      • Annexin A1 antibody
      • Annexin I (lipocortin I) antibody
      • Annexin I antibody
      • Annexin-1 antibody
      • AnnexinA1 antibody
      • AnnexinI antibody
      • ANX 1 antibody
      • ANX A1 antibody
      • ANX1 antibody
      • ANXA 1 antibody
      • ANXA1 antibody
      • ANXA1 protein antibody
      • ANXA1_HUMAN antibody
      • Calpactin 2 antibody
      • Calpactin II antibody
      • Calpactin-2 antibody
      • CalpactinII antibody
      • Chromobindin 9 antibody
      • Chromobindin-9 antibody
      • Chromobindin9 antibody
      • HGNC:533 antibody
      • Lipocortin 1 antibody
      • Lipocortin I antibody
      • Lipocortin1 antibody
      • LipocortinI antibody
      • LPC 1 antibody
      • LPC1 antibody
      • p35 antibody
      • Phospholipase A2 inhibitory protein antibody
      see all

    Images

    • Ab41830 staining human Annexin I in human placenta by formalin fixed paraffin embedded immunohistochemistry at 1/25 dilution.

    References

    ab41830 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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