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Overview

  • Product nameAnnexin A1 peptideSee all Annexin A1 proteins and peptides ...
  • Protein descriptionSynthetic peptide derived from within residues 200 - 300 of Human Annexin A1.(Note: the amino acid sequence is proprietary)This peptide was used as an immunogen for ab47661 - Annexin A1 antibody.
  • Protein length346 amino acids

    • Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferInformation available upon request.
  • Concentration information loading...
  • Research Areas

    • Applications

  • Application notesThis peptide can be used with studies using ab46686 and ab47661.

    • Protein info

    • Alternative names
        Annexin 1Annexin A1Annexin I
        Annexin I (lipocortin I)Annexin-1AnnexinA1AnnexinIANX 1ANX A1ANX1ANXA 1ANXA1ANXA1 proteinANXA1_HUMANCalpactin 2Calpactin IICalpactin-2CalpactinIIChromobindin 9Chromobindin-9Chromobindin9HGNC:533Lipocortin 1Lipocortin ILipocortin1LipocortinILPC 1LPC1p35Phospholipase A2 inhibitory protein
      see all
  • FunctionCalcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity.
  • Sequence similaritiesBelongs to the annexin family.
    Contains 4 annexin repeats.
  • DomainA pair of annexin repeats may form one binding site for calcium and phospholipid.
  • Post-translational
    modifications    Phosphorylated by protein kinase C, epidermal growth factor receptor/kinase and TRPM7. Phosphorylation results in loss of the inhibitory activity.
  • Cellular localizationNucleus. Cytoplasm. Cell projection > cilium. Basolateral cell membrane. Found in the cilium, nucleus and basolateral cell membrane of ciliated cells in the tracheal endothelium (By similarity). Found in the cytoplasm of type II pneumocytes and alveolar macrophages.

    • Target information above from: UniProt accession P04083 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for Annexin A1 peptide (ab47660)

    ab47660 has not yet been referenced specifically in any publications.

    Publishing research using ab47660 ? Please let us know so that we can cite the reference in this datasheet

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