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Overview

  • Product nameAnnexin II peptideSee all Annexin A2 proteins and peptides ...
  • Protein descriptionSynthetic peptide derived from within residues 150 - 250 of Human Annexin II.(Note: the amino acid sequence is proprietary)This peptide was used as an immunogen for ab41803 - Annexin II antibody.
  • Protein length336 amino acids

    • Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferInformation available upon request.
  • Concentration information loading...
  • Research Areas

    • Applications

  • Application notesThis peptide can be used with studies using ab40943 and ab41803.

    • Protein info

    • Alternative names
        Annexin A2Annexin IIAnnexin-2
        ANX 2ANX2ANX2L4ANXA2ANXA2_HUMANarylsulfatase BCAL1HCalpactin I heavy chaincalpactin I heavy polypeptide (p36)Calpactin-1 heavy chainchromobindin 8Chromobindin-8LIP2Lipocortin IILPC2LPC2DP36P36 proteinPAP-IVplacental anticoagulant protein IVProtein I
      see all
  • FunctionCalcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response.
  • Sequence similaritiesBelongs to the annexin family.
    Contains 4 annexin repeats.
  • DomainA pair of annexin repeats may form one binding site for calcium and phospholipid.
  • Post-translational
    modifications    Phosphorylation of Tyr-24 enhances heat stress-induced translocation to the cell surface.
    ISGylated.
  • Cellular localizationSecreted > extracellular space > extracellular matrix > basement membrane. Melanosome. In the lamina beneath the plasma membrane. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Translocated from the cytoplasm to the cell surface through a Golgi-independent mechanism.

    • Target information above from: UniProt accession P07355 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for Annexin II peptide (ab41802)

    ab41802 has not yet been referenced specifically in any publications.

    Publishing research using ab41802 ? Please let us know so that we can cite the reference in this datasheet

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