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Annexin V-Cy3 Apoptosis Detection Reagent (ab14143)

Submit an Abreview Q&A (1)Specific References (4)

Overview

  • Product nameAnnexin V-Cy3 Apoptosis Detection ReagentSee all Annexin V reagents ...
  • Tested applicationsFluorescence Microscopy, Flow Cyt more details

    • Properties

  • FormLiquid
  • Storage instructionsStore at -20°C.
  • Concentration information loading...
  • Research Areas
  • FunctionThis protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.
  • Sequence similaritiesBelongs to the annexin family.
    Contains 4 annexin repeats.
  • DomainA pair of annexin repeats may form one binding site for calcium and phospholipid.

    • Target information above from: UniProt accession P08758 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
    • Alternative names
        Anchorin CIIAnnexin 5Annexin A5
        Annexin VAnnexin-5Annexin5AnnexinA5AnnexinVANX 5ANX A5ANX5ANXA5ANXA5_HUMANCalphobindin ICBP ICBP-IEndonexin IIENX 2ENX2Lipocortin VPAP IPAP-IPlacental anticoagulant protein 4Placental anticoagulant protein IPP 4PP4RPRGL3Thromboplastin inhibitorVAC alphaVAC-alphaVascular anticoagulant alphaVascular anticoagulant-alpha
      see all

    Applications

    Our Abpromise guarantee covers the use of ab14143 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    Fluorescence Microscopy Fluorescence Microscopy: Use at an assay dependent concentration.
    Flow Cyt Flow Cyt: Use at an assay dependent dilution.

    Protocols

    References for Annexin V-Cy3 Apoptosis Detection Reagent (ab14143)

    This product has been referenced in:
    • Schuhmann D  et al. Interfering with interferon-? signalling in intestinal epithelial cells: selective inhibition of apoptosis-maintained secretion of anti-inflammatory interleukin-18 binding protein. Clin Exp Immunol 163:65-76 (2011). Read more (PubMed: 21078084) »
    • Thuwanut P  et al. The effects of antioxidants on semen traits and in vitro fertilizing ability of sperm from the flat-headed cat (Prionailurus planiceps). Theriogenology 76:115-25 (2011). Read more (PubMed: 21396691) »

    See all 4 Publications for this product

    Publishing research using ab14143 ? Please let us know so that we can cite the reference in this datasheet

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    Submit an Abreview for ab14143 Submit a Question for ab14143

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    Regarding you annexin V-Cy3 conjugate, I would like to know the following: 1) What is the source of your annexin? (e.g. human placenta?) 2) Is the annexin in ab14143 purified and labeled in Abcam labs? Or is the annexin V-y3 conjugate purchased fr...

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    Thank you for your enquiry. Please find below the answers to your questions. 1) The source of the annexin is human recombinant protein. 2) This product is from an originator outside of Abcam. Unfortunately, due to company policies and supplier...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"