Annexin V-PE-Cy5 Apoptosis Detection Reagent (ab14158)
- Product nameAnnexin V-PE-Cy5 Apoptosis Detection ReagentSee all Annexin V reagents ...
- Tested applicationsFluorescence Microscopy, Flow Cyt more details
- Species reactivityReacts with: Mouse
- General notes
Annexin V-PE-Cy5 is a bright fluorescent reagent for detecting of the early stages of apoptosis. During apoptosis, phosphatidylserine (PS) is translocated from the cytoplasmic face of the plasma membrane to the cell surface. Annexin V has a strong, Ca2+ dependent affinity for PS and therefore serves as a probe for detecting apoptosis.
- Storage bufferPreservative: 0.02% Sodium Azide
Constituents: 1% BSA, 0.25mg/ml PBS
- Concentration information loading...
- Research Areas
- FunctionThis protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.
- Sequence similaritiesBelongs to the annexin family.
Contains 4 annexin repeats.
- DomainA pair of annexin repeats may form one binding site for calcium and phospholipid.
- Anchorin CII
- Annexin 5
- Annexin A5
- Annexin V
- ANX 5
- ANX A5
- Calphobindin I
- CBP I
- Endonexin II
- ENX 2
- Lipocortin V
- PAP I
- Placental anticoagulant protein 4
- Placental anticoagulant protein I
- PP 4
- Thromboplastin inhibitor
- VAC alpha
- Vascular anticoagulant alpha
- Vascular anticoagulant-alpha
Our Abpromise guarantee covers the use of ab14158 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Fluorescence Microscopy||Fluorescence Microscopy: Use at an assay dependent concentration.|
|Flow Cyt||Flow Cyt: Use at an assay dependent dilution.|
References for Annexin V-PE-Cy5 Apoptosis Detection Reagent (ab14158)
This product has been referenced in:
- Naka K et al. TGF-beta-FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemia. Nature 463:676-80 (2010). ICC/IF ; Mouse . Read more (PubMed: 20130650) »
- Shah MD et al. Flow cytometric measurement of microparticles: pitfalls and protocol modifications. Platelets 19:365-72 (2008). Read more (PubMed: 18791943) »