Overview

  • Product nameAnti-Annexin VI p70 antibody
  • Description
    Rabbit polyclonal to Annexin VI p70
  • Tested applicationsWB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    A synthetic peptide derived from N-terminus of human Annexin VI protein

Properties

Applications

Our Abpromise guarantee covers the use of ab131728 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 76 kDa.
IHC-P Use at an assay dependent dilution.

Target

  • RelevanceThe Annexins are abundant, evolutionarily conserved proteins, which are distinguished by their ability to bind reversibly to phospholipids and cell membranes in physiologic concentrations of calcium ion. Three members of this protein family with apparent molecular masses of 67 kD, 35 kD, and 32.5 kD have been purified to homogeneity. The protein p68 is a member of a family of proteins that bind membrane or cytoskeleton in a Ca(2+)-dependent manner. They are characterized by homologous amino acid sequences that are present in multiple copies in each protein. The family is variously known as calelectrins, annexins, calpactins, endonexins, and lipocortins. p68 is an intracellular monomeric protein of approximately 68 kDa MW. Annexins self-associate to form trimers which further assemble into sheets that cover the membrane surface and alter properties such as fluidity and permeability. This submembranous skeleton alters integral protein functions such as ion transport properties and shields the surface from phospholipid binding proteins such as phospholipases and protein kinase C.
  • Cellular localizationCytoplasmic
  • Database links
  • Alternative names
    • 67 kDa calelectrin antibody
    • Annexin 6 antibody
    • Annexin VI antibody
    • Calcium-binding protein p68 antibody
    • Calelectrin antibody
    • Calphobindin II antibody
    • Chromobindin 20 antibody
    • Lipocortin VI antibody
    • p68 antibody
    • p70 antibody
    • Protein III antibody
    see all

References for Anti-Annexin VI p70 antibody (ab131728)

ab131728 has not yet been referenced specifically in any publications.

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