Overview
- Product nameAnti-Apc2 antibody - BSA and Azide freeSee all Apc2 primary antibodies ...
- DescriptionRabbit polyclonal to Apc2 - BSA and Azide free
- Tested applicationsWB more details
- Species reactivityReacts with: Mouse, Human
- Immunogen
Synthetic peptide from the C terminus of human Apc2
- Positive controlHeLa cells.
Properties
- FormLiquid
- Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
- Storage bufferPreservative: None
Constituents: 10mM PBS, pH 7.4 -
Concentration information loading... - PurityProtein A purified
- Purification notesab77563 is purified from rabbit anti serum by Protein A chromatography.
- Clonality Polyclonal
- IsotypeIgG
- Research Areas
Applications
Our Abpromise guarantee covers the use of ab77563 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| WB |
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
- FunctionComponent of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
- PathwayProtein modification; protein ubiquitination.
- Sequence similaritiesBelongs to the cullin family.
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Database links
- Entrez Gene: 29882 Human
- Entrez Gene: 99152 Mouse
- Omim: 606946 Human
- SwissProt: Q9UJX6 Human
- SwissProt: Q8BZQ7 Mouse
- Unigene: 434898 Human
- Unigene: 533262 Human
- Unigene: 291624 Mouse
Target information above from: UniProt accession
Q9UJX6
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010)
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Alternative names
- ANAPC2 antibodyAnaphase promoting complex subunit 2 antibodyAnaphase-promoting complex subunit 2 antibody
- ANC2_HUMAN antibodyAPC2 antibodyCyclosome subunit 2 antibodyKIAA1406 antibodyOTTHUMP00000022692 antibodyRP11 350O14.5 antibody
see all
References for Anti-Apc2 antibody - BSA and Azide free (ab77563)
ab77563 has not yet been referenced specifically in any publications.
