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Anti-Apg10 antibody (ab64125)

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Overview

Product name

Anti-Apg10 antibody
See all Apg10 products (6) ...

Description

Rabbit polyclonal to Apg10

Tested applications

WB, IHC-P, IHC-Frmore details

Cross reactivity

Reacts with

Human

Immunogen

synthetic peptide as a part of human autophagy-related protein 10 (ATG10, APG10) conjugated to immunogenic carrier protein

Properties

Form

Liquid

Storage instructions

Store at +4°C short term (1-2 weeks). Add glycerol to a final volume of 50%, aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: None
Constituents: PBS, whole serum

Purity

Whole antiserum

Clonality

Polyclonal

Isotype

IgG

Research areas

Cardiovascular >> Heart >> Autophagy >> APG gene products
Cancer >> Oncoproteins/suppressors >> Tumor suppressors >> Other
Neuroscience >> Neurology process >> Neurodegenerative disease >> Other
Cell Biology >> Proteolysis / Ubiquitin >> Proteasome / Ubiquitin >> Ub-like Proteins

Applications

Show applications key

Our Abpromise guarantee covers the use of ab64125 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ShowHide

    WB

     WB: 1/100 - 1/3000.Predi...Read more →

    WB: 1/100 - 1/3000.Predicted molecular weight: 25 kDa.

  • ShowHide

    IHC-P

     IHC-P: 1/100 - 1/3000.Pe...Read more →

    IHC-P: 1/100 - 1/3000.Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

  • IHC-Fr

     IHC-Fr: 1/100 - 1/3000.

    IHC-Fr: 1/100 - 1/3000.

Target

Function

E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for autophagy. Likely serves as an ATG5-recognition molecule. Not involved in ATG12 conjugation to ATG3.

Sequence similarities

Belongs to the ATG10 family.

Cellular localization

Cytoplasm.

Target information above from: UniProt accessionQ9H0Y0 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • Apg 10 antibody
  • APG 10L antibody
  • APG10 antibody
  • APG10 autophagy 10 like antibody
  • APG10 like antibody
  • APG10-like antibody
  • APG10L antibody
  • ATG 10 antibody
  • ATG10 antibody
  • ATG10 autophagy related 10 homolog (S. cerevisiae) antibody
  • ATG10 autophagy related 10 homolog antibody
  • ATG10_HUMAN antibody
  • Autophagy related protein 10 antibody
  • Autophagy-related protein 10 antibody
  • DKFZP586I0418 antibody
  • FLJ13954 antibody
  • pp12616 antibody
  • Ubiquitin-like-conjugating enzyme ATG10 antibody
see all

Database links

References for Anti-Apg10 antibody (ab64125)

This product has been referenced in:

  • Crews Let al. Selective Molecular Alterations in the Autophagy Pathway in Patients with Lewy Body Disease and in Models of alpha-Synucleinopathy. PLoS One 5:e9313 (2010). WB, IHC-P; Human, Mouse.Read more (PubMed: 20174468) »

See 1 publication for this product

Publishing research using ab64125? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"