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Product name
Apocynin
Description
Selective NADPH-oxidase inhibitor
Biological description
Selective NADPH-oxidase inhibitor (IC50 = 10 µM). Inhibits production of reactive oxygen species. Also elicits a range of in vitro and in vivo anti-inflammatory effects.
Purity
> 99%
General notes
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Properties
Chemical name
4'-Hydroxy-3'-methoxyacetophenone
Molecular Weight
166.17
Chemical structure
Molecular formula
C9H10O3
CAS Number
498-02-2
Solubility
Soluble in DMSO to 100 mM and in ethanol to 100 mM
Storage instructions
Store at room temperature.
Research areas
Biochemicals >> Pharmacology >> Enzymes >> Oxidases >> NADPH oxidase >> Inhibitors
Biochemicals >> Chemical Type >> Biochemicals
References for Apocynin (ab120615)
This product has been referenced in:
- Genovese T et al. Modulation of NADPH oxidase activation in cerebral ischemia/reperfusion injury in rats. Brain Res 1372:92-102 (2011).Read more (PubMed: 21138737) »
- Impellizzeri D et al. Effect of apocynin, a NADPH oxidase inhibitor, on acute lung inflammation. Biochem Pharmacol 81:636-48 (2011).Read more (PubMed: 21147071) »
See all 3 publications for this product
Publishing research using ab120615? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"