Overview

  • Product nameAnti-Apolipoprotein A II antibodySee all Apolipoprotein A II primary antibodies ...
  • Description
    Goat polyclonal to Apolipoprotein A II
  • SpecificityTypically less than 1% cross reactivity against other types of apoLipoprotein was detected by ELISA. This antibody reacts with human apoLipoprotein A-II and has negligible cross-reactivity with Type A-I, B, C-I, C-II, C-III, E and J apoLipoproteins.
  • Tested applicationsDot Blot, ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length native apoLipoprotein Type A-II (purified).

  • General notesThis antibody has been used to determine that atherosclerotic lesions in the human aorta contain considerable amounts of lipoproteins. These lipoproteins were observed to be complexed with components of the extracellular matrix (especially LDL and proteoglycans). The role of these matrix-lipoprotein complexes is not entirely clear, however, animal models of atherosclerosis have shown that increased cellular proliferation and increased production of extracellular matrix components occur following injury to the intimal layer of the aorta.

Properties

Applications

Our Abpromise guarantee covers the use of ab7615 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Dot Blot 1/5000 - 1/10000.
ELISA 1/4000 - 1/8000.
WB Use at an assay dependent dilution.

Target

  • FunctionMay stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism.
  • Tissue specificityPlasma; synthesized in the liver and intestine.
  • Sequence similaritiesBelongs to the apolipoprotein A2 family.
  • Post-translational
    modifications
    Phosphorylation sites are present in the extracelllular medium.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • APO A2 antibody
    • Apo AII antibody
    • Apo-AII antibody
    • APOA 2 antibody
    • ApoA II antibody
    • ApoA-II antibody
    • APOA2 antibody
    • APOA2_HUMAN antibody
    • APOAII antibody
    • Apolipoprotein A II antibody
    • Apolipoprotein A-II(1-76) antibody
    • Apolipoprotein A2 antibody
    • Apolipoprotein AII antibody
    • ApolipoproteinA II antibody
    • OTTHUMP00000032244 antibody
    see all

References for Anti-Apolipoprotein A II antibody (ab7615)

This product has been referenced in:
  • Kasthuri RS  et al. Extraordinary apolipoprotein oxidation in chronic hepatitis C and liver cirrhosis. Mol Cell Proteomics : (2007). WB ; Human . Read more (PubMed: 17709793) »

See 1 Publication for this product

Product Wall

Thank you for your enquiry and your interest in our products. We would like to confirm that this antibody can bind ApoAII in intact HDL particles.

The immunogen is derived from human plasma. So far, it has only been tested for cross-reactivity with human.

17.4 kDa.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"