Anti-Apolipoprotein CI antibody (Biotin) (ab27634)

Overview

• Product name
  Anti-Apolipoprotein CI antibody (Biotin)
  See all Apolipoprotein CI primary antibodies
• Description
  Goat polyclonal to Apolipoprotein CI (Biotin)
• Conjugation
  Biotin
• Specificity
  Specifically binds to human Apolipoprotein C-I.
• Tested applications
  Suitable for: WB, ELISAmore details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Full length native Apo CI protein (purified) (Human)

Properties

• Form
  Liquid
• Storage instructions
  Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
• Storage buffer
  Preservative: 0.02% Sodium Azide
  Constituents: 50% Glycerol, 75mM Sodium chloride, 75mM PBS, pH 7.2
• Concentration information loading...
• Purity
  Immunogen affinity purified
• Purification notes
  Purified by human Apolipoprotein C-I-Sepharose^TM affinity column.
• Clonality
  Polyclonal
• Isotype
  IgG
• Research areas
  • Cardiovascular
  • Lipids / Lipoproteins
  • Lipoproteins/Apolipoproteins
  • Lipoproteins

  • Cardiovascular
  • Lipids / Lipoproteins
  • Lipoproteins/Apolipoproteins

  • Cardiovascular
  • Lipids / Lipoproteins
  • Fatty Acids
  • Binding proteins

  • Signal Transduction
  • Metabolism
  • Lipid metabolism

  • Cardiovascular
  • Atherosclerosis
  • Lipoprotein metabolism

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Lipid and lipoprotein metabolism
  • Lipoprotein metabolism

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Lipid and lipoprotein metabolism
  • Fatty acids

  • Metabolism
  • Types of disease
  • Cancer

  • Metabolism
  • Types of disease
  • Heart disease

  • Metabolism
  • Pathways and Processes
  • Redox metabolism
  • Fatty acid oxidation

Associated products

• Compatible Secondaries
  • Donkey Anti-Goat IgG H&L (Alexa Fluor® 488) (ab150129)
  • Donkey Anti-Goat IgG H&L (HRP) (ab205723)

Applications

Target

• Function
  Appears to modulate the interaction of APOE with beta-migrating VLDL and inhibit binding of beta-VLDL to the LDL receptor-related protein. Binds free fatty acids and reduces their intracellular esterification.
• Tissue specificity
  Synthesized mainly in liver and to a minor degree in intestine. Secreted in plasma.
• Sequence similarities
  Belongs to the apolipoprotein C1 family.
• Cellular localization
  Secreted.

• Target information above from: UniProt accession P02654 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• Database links
  • Entrez Gene: 341 Human
  • Omim: 107710 Human
  • SwissProt: P02654 Human
  • Unigene: 110675 Human
• Alternative names
  • APO C1 antibody
  • Apo CI antibody
  • Apo-CIB antibody

  • Apo-CIB' antibody
  • APOC 1 antibody
  • ApoC I antibody
  • ApoC-IB antibody
  • ApoC-IB' antibody
  • APOC1 antibody
  • APOC1_HUMAN antibody
  • APOC1B antibody
  • Apolipoprotein C I antibody
  • Apolipoprotein C I variant I antibody
  • Apolipoprotein C-I antibody
  • Apolipoprotein C1 antibody
  • Apolipoprotein CI antibody
  • ApolipoproteinC I antibody
  • ApolipoproteinCI antibody
  • Truncated apolipoprotein C-I antibody

  see all

Protocols

• Western blot protocols