Overview

  • Product name
    Anti-Apolipoprotein CI antibody
    See all Apolipoprotein CI primary antibodies
  • Description
    Goat polyclonal to Apolipoprotein CI
  • Specificity
    ab104446 recognizes Human Apolipoprotein CI in plasma and lipoproteins. It does not cross-react with plasma Apo A-I, Apo A-II, Apo B-100, Apo C-II, Apo C-III and Apo-E.
  • Tested applications
    Suitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length native protein (purified) (Human)

  • Positive control
    • Human Liver tissue

Applications

Our Abpromise guarantee covers the use of ab104446 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/10000. Predicted molecular weight: 9 kDa.
ELISA 1/100 - 1/10000.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Appears to modulate the interaction of APOE with beta-migrating VLDL and inhibit binding of beta-VLDL to the LDL receptor-related protein. Binds free fatty acids and reduces their intracellular esterification.
  • Tissue specificity
    Synthesized mainly in liver and to a minor degree in intestine. Secreted in plasma.
  • Sequence similarities
    Belongs to the apolipoprotein C1 family.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • APO C1 antibody
    • Apo CI antibody
    • Apo-CIB antibody
    • Apo-CIB' antibody
    • APOC 1 antibody
    • ApoC I antibody
    • ApoC-IB antibody
    • ApoC-IB' antibody
    • APOC1 antibody
    • APOC1_HUMAN antibody
    • APOC1B antibody
    • Apolipoprotein C I antibody
    • Apolipoprotein C I variant I antibody
    • Apolipoprotein C-I antibody
    • Apolipoprotein C1 antibody
    • Apolipoprotein CI antibody
    • ApolipoproteinC I antibody
    • ApolipoproteinCI antibody
    • Truncated apolipoprotein C-I antibody
    see all

Images

  • ab104446, at 5 ug/ml, staining Apolipoprotein CI in formalin-fixed, paraffin-embedded Human Liver by Immunohistochemistry, using a biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

References

ab104446 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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