The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notesConjugation: Use at an assay dependent dilution.
ELISA: 1/2500 - 1/20000.
WB: 1/2500 - 1/20000. Predicted molecular weight: 9 kDa. Dilution optimised using Chromogenic detection.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionAppears to modulate the interaction of APOE with beta-migrating VLDL and inhibit binding of beta-VLDL to the LDL receptor-related protein. Binds free fatty acids and reduces their intracellular esterification.
Tissue specificitySynthesized mainly in liver and to a minor degree in intestine. Secreted in plasma.
Sequence similaritiesBelongs to the apolipoprotein C1 family.