Anti-Apolipoprotein E antibody [D6E10] (ab1906)

The protocol tips did not help. I would like a refund.

ANSWER:

Your credit note ID is xxxx. I am sorry that this antibody did not perform as stated on the datasheet. I have asked our accounting department to issue a credit note for you, which can be redeemed against the invoice of a future order by passing it on to your purchasing department. To avoid confusion, please ensure your accounts department is aware of how the credit note is being used. If you have questions on how to use the credit note, please contact our accounting department. Our accounting department can be contacted by email at us.credits@abcam.com or by telephone using the information at the Contact Us link in the top right corner of our website. Please refer to the credit note ID in any correspondence with our accounting department. The credit note ID is for your reference only and does not automatically guarantee the credit. I hope this experience will not prevent you from purchasing other products from us in the future. Our Scientific Support team is always at your service, should you require further expert advice

Have you any response from the lab about offering a blocking peptide to this?

ANSWER:

Once again, thank you for contacting Abcam.I am sorry that you have been getting less than expected results using ab1906. I was able to speak with the lab today regarding blocking peptide for this product. Unfortunately at this time we do not offer this. I sincerely hope that the suggestions that I made last week have improved your results using ab1906. Please contact me if there is anything else that I might be able to do for you.

Based on the antibody datasheet, it is raised against an epitope spanning across amino acid 158 of ApoE. I understand that there is a point mutation under this aa giving the three isoforms of apoE. Is this antibody able to detect all three isoform of ApoE or just selective isoform. May I please ask if you are able to clarify?

ANSWER:

Yes, the ab1906 anti-Apo-E antibody (clone D6E10) recognizes the isoforms E2, E3 and E4 of apolipoprotein E.