Anti-Archaemetzincin 2 antibody (ab59926)

Overview

• Product nameAnti-Archaemetzincin 2 antibodySee all Archaemetzincin 2 primary antibodies ...
• Description
  Rabbit polyclonal to Archaemetzincin 2
• Specificityab59926 recognizes the 424, 360, 302 and 209 amino acid forms of archaemetzincins2, and not the 325 and 189 amino acid forms. We have a range of domain specific antibodies for this target. For a full list please see all archaemetzincins2 antibodies.
• Tested applicationsWB more details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Synthetic peptide based on the propeptide domain of human archaemetzincins2. Immunizing peptide available on request - please contact a member of staff to ask for availability.

Properties

• FormLiquid
• Storage instructionsStore at -20°C. Stable for 12 months at -20°C
• Storage bufferPreservative: 0.05% Sodium Azide
  Constituents: 50% Glycerol, PBS, 500mM Sodium chloride, pH 7.4
• Concentration information loading...
• PurityImmunogen affinity purified
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Cell Biology
  • Proteolysis / Ubiquitin
  • Proteolytic enzymes
  • Other proteases

Applications

Target

• FunctionZinc metalloprotease. Exhibits activity against angiotensin-3 in vitro. Does not hydrolyze either neurogranin or angiotensin-2.
• Tissue specificityPredominantly expressed in heart and testis. Also expressed at lower levels in kidney, liver, pancreas, lung, brain and placenta. Expressed in fetal tissues such as kidney, liver, lung and brain.
• Sequence similaritiesBelongs to the peptidase M54 family.

Target information above from: UniProt accession Q86W34 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 51321 Human
  • SwissProt: Q86W34 Human
  • Unigene: 293560 Human

• Alternative names
  AMZ2 antibodyAMZ2_HUMAN antibodyArchaemetzincin 2 antibody

  Archaemetzincin-2 antibodyArcheobacterial metalloproteinase like protein 2 antibodyArcheobacterial metalloproteinase-like protein 2 antibody

  see all

Anti-Archaemetzincin 2 antibody images

• 

  Western blot - Archaemetzincin 2 antibody - Propeptide domain (ab59926)
  All lanes : Anti-Archaemetzincin 2 antibody (ab59926) at 1/1000 dilution
  
  Lane 1 : Whole cell lysate prepared from Madin Darby canine kidney (MDCK) cells (1:4) (serum free)
  Lane 2 : Whole cell lysate prepared from Madin Darby canine kidney (MDCK) cells (1:4) (treated with TPA)
  Lane 3 : Whole cell lysate prepared from Madin Darby canine kidney (MDCK) cells (1:4) (treated with IL1-beta)
  Lane 4 : Whole cell lysate prepared from Madin Darby canine kidney (MDCK) cells (1:4) (treated with TNF-alpha)
  
  Lysates/proteins at 20 µl per lane.
  
  
  Predicted band size : 41 kDa