You have changed your country from  to  . Please be aware that this will change the currency in the purchasing process.

Overview

  • Product nameAnti-Arg 3.1 antibodySee all Arg 3.1 primary antibodies ...
  • Description
    Sheep polyclonal to Arg 3.1
  • Specificityab62142 is specific for Arg3.1.
  • Tested applicationsWB, IHC-P, IHC-Fr more details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptides (a pentamer) as parts of human, mouse and rat Arg3.1.

Properties

Applications

Our Abpromise guarantee covers the use of ab62142 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB WB: Use a concentration of 1 - 10 µg/ml. Predicted molecular weight: 45 kDa. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
IHC-P IHC-P: Use a concentration of 1 - 10 µg/ml.
IHC-Fr IHC-Fr: Use a concentration of 1 - 10 µg/ml.

Target

  • FunctionRequired for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration.
  • Sequence similaritiesBelongs to the ARC/ARG3.1 family.
  • Cellular localizationCytoplasm > cytoskeleton. Endosome. Cytoplasmic vesicle > secretory vesicle > acrosome. Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Cell projection > dendrite. Cell projection > dendritic spine. Cell junction > synapse. Associated with the cell cortex of neuronal soma and dendrites. Enriched in postsynaptic density of dendritic spines. Associated with the sperm tail (By similarity). Enriched on the plasma membrane.

    • Target information above from: UniProt accession Q7LC44 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
    see all
  • Alternative names
      Activity regulated cytoskeletal associated protein antibodyActivity regulated cytoskeletal protein antibodyActivity regulated gene 3.1 protein homolog antibody
      Activity-regulated cytoskeleton-associated protein antibodyActivity-regulated gene 3.1 protein homolog antibodyArc antibodyARC/ARG3.1 antibodyARC_HUMAN antibodyArg3.1 antibodyKIAA0278 antibody
    see all

References for Anti-Arg 3.1 antibody (ab62142)

ab62142 has not yet been referenced specifically in any publications.

Publishing research using ab62142 ? Please let us know so that we can cite the reference in this datasheet

Product Wall

Submit an Abreview for ab62142 Submit a Question for ab62142

There are currently no Abreviews or Questions for ab62142.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"