Anti-Artemin antibody - Aminoterminal end (ab45506)

Overview

  • Product name
    Anti-Artemin antibody - Aminoterminal end
    See all Artemin primary antibodies
  • Description
    Rabbit polyclonal to Artemin - Aminoterminal end
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide (Human) corresponds with the N terminus of human Artemin.

  • Positive control
    • human dorsal root ganglia/CNS

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • Purification notes
    ab45506 is a purified IgG.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab45506 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 20 kDa (predicted molecular weight: 23 kDa).

Target

  • Function
    Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain.
  • Tissue specificity
    Ubiquitous. Expressed at high levels in peripheral tissues including prostate, placenta, pancreas, heart, kidney, pituitary gland, lung and testis. Expressed at low levels in the brain.
  • Sequence similarities
    Belongs to the TGF-beta family. GDNF subfamily.
  • Developmental stage
    Expressed during embryogenesis. High level expression seen in fetal kidney and lung while a low level expression seen in the fetal brain.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Artemin antibody
    • Artn antibody
    • ARTN_HUMAN antibody
    • Enovin antibody
    • EVN antibody
    • NBN antibody
    • Neublastin antibody
    • Neurotrophic factor antibody
    see all

Images

  • Anti-Artemin antibody - Aminoterminal end (ab45506) at 1/500 dilution (incubated over night at 4C.) + dorsal root ganglia/CNS preparation.
    Developed using the ECL technique

    Predicted band size : 23 kDa

References

ab45506 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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