Anti-Asialoglycoprotein Receptor 1 antibody (ab127896)

Overview

• Product nameAnti-Asialoglycoprotein Receptor 1 antibodySee all Asialoglycoprotein Receptor 1 primary antibodies ...
• Description
  Rabbit polyclonal to Asialoglycoprotein Receptor 1
• Tested applicationsWB more details
• Species reactivity
  Reacts with: Mouse, Human
  
• Immunogen

  Recombinant fragment, corresponding to a region within amino acids 25-241 of Human Asialoglycoprotein Receptor 1 (P07306).

• Positive controlHuman HepG2 and Mouse NIH 3T3 cell lysates.

Properties

• FormLiquid
• Storage instructionsStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Storage bufferpH: 7.00
  Preservative: 0.01% Thimerosal (merthiolate)
  Constituents: 0.75% Glycine, 1.21% Tris, 20% Glycerol
• Concentration information loading...
• PurityImmunogen affinity purified
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Signal Transduction
  • Protein Trafficking
  • Organelle Proteins

Applications

Target

• FunctionMediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
• Tissue specificityExpressed exclusively in hepatic parenchymal cells.
• Sequence similaritiesContains 1 C-type lectin domain.
• Post-translational
  modificationsPhosphorylated on a cytoplasmic Ser residue.
• Cellular localizationMembrane.

Target information above from: UniProt accession P07306 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 432 Human
  • Entrez Gene: 11889 Mouse
  • Omim: 108360 Human
  • SwissProt: P07306 Human
  • SwissProt: P34927 Mouse
  • Unigene: 12056 Human
  • Unigene: 6559 Mouse

• Alternative names
  ASGP-R 1 antibodyASGPR 1 antibodyASGPR antibody

  ASGPR1 antibodyAsgr1 antibodyASGR1_HUMAN antibodyAsialoglycoprotein receptor 1 antibodyC type lectin domain family 4 member H1 antibodyC-type lectin domain family 4 member H1 antibodyCLEC4H1 antibodyHepatic lectin H1 antibodyHL-1 antibody

  see all

Anti-Asialoglycoprotein Receptor 1 antibody images

• 

  Western blot - Anti-Asialoglycoprotein Receptor 1 antibody (ab127896)
  Anti-Asialoglycoprotein Receptor 1 antibody (ab127896) at 1/3000 dilution + HepG2 whole cell lysate at 30 µg
  developed using the ECL technique
  
  Predicted band size : 33 kDa
  
• 

  Western blot - Anti-Asialoglycoprotein Receptor 1 antibody (ab127896)
  Anti-Asialoglycoprotein Receptor 1 antibody (ab127896) at 1/1000 dilution + Mouse NIH 3T3 whole cell lysate at 30 µg
  developed using the ECL technique
  
  Predicted band size : 33 kDa