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Overview

  • Product nameAnti-Attractin antibodySee all Attractin primary antibodies ...
  • Description
    Rabbit polyclonal to Attractin
  • Tested applicationsWB more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 1391-1421 of Human Attractin (NP_647537.1, NP_647538.1).

  • Positive controlA549 cell line lysates.

Properties

  • FormLiquid
  • Storage instructionsStore at 4°C (up to 6 months). For long term storage store at -20°C
  • Storage bufferPreservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesThis antibody is purified through a protein A column, followed by peptide affinity purification.
  • Clonality Polyclonal
  • IsotypeIgG
  • Research Areas

Applications

Our Abpromise guarantee covers the use of ab129503 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB WB: 1/100 - 1/500. Predicted molecular weight: 159 kDa.

Target

  • FunctionInvolved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines. May play a role in melanocortin signaling pathways that regulate energy homeostasis and hair color. Low-affinity receptor for agouti (By similarity). Has a critical role in normal myelination in the central nervous system.
  • Tissue specificityIsoform 2 is detected in plasma (at protein level). Expressed and secreted by activated T lymphocytes. Expressed at low to moderate levels in peripheral blood leukocytes, spleen, lymph node, tonsil, bone marrow and fetal liver. At very low levels found in thymus. Isoform 2 is the major isoform in peripheral blood leukocytes.
  • Sequence similaritiesContains 1 C-type lectin domain.
    Contains 1 CUB domain.
    Contains 1 EGF-like domain.
    Contains 6 Kelch repeats.
    Contains 2 laminin EGF-like domains.
    Contains 4 PSI domains.
  • Post-translational
    modifications    Heavily glycosylated.
  • Cellular localizationSecreted and Cell membrane.

    • Target information above from: UniProt accession O75882 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
    • Alternative names
        ATRN antibodyATRN_HUMAN antibodyattractin 2 antibody
        Attractin antibodyDPPT L antibodyDPPT-L antibodyKIAA0548 antibodyMahogany homolog antibodymahogany protein antibodyMGCA antibody
      see all

    Anti-Attractin antibody images

    • Western blot - Anti-Attractin antibody (ab129503)
      Western blot - Anti-Attractin antibody (ab129503)
      Anti-Attractin antibody (ab129503) at 1/100 dilution + A549 cell line lysates at 35 µg

      Predicted band size : 159 kDa

    References for Anti-Attractin antibody (ab129503)

    ab129503 has not yet been referenced specifically in any publications.

    Publishing research using ab129503 ? Please let us know so that we can cite the reference in this datasheet

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