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Anti-Axl antibody (ab32828)

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Overview

Product name

Anti-Axl antibody
See all Axl products (8) ...

Description

Rabbit polyclonal to Axl

Tested applications

WBmore details

Cross reactivity

Reacts with

Mouse, Rat, Human, Monkey

Immunogen

Synthetic peptide: DSCSCLTAAEVHPAGRYVLCPS, corresponding to C terminal amino acids 843-864 of Human Axl. The peptide was post translationaly modified to achieve proper orientation and antigenicity.

DSCSCLTAAE VHPAGRYVLC PS

Run BLAST with BLAST the sequence with ExPASyRun BLAST with BLAST the sequence with NCBI

Positive control

Rat testis extracts.

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Storage buffer

Preservative: 0.02% Sodium Azide.

Concentration

Concentration information loading...

Purity

Protein A purified

Clonality

Polyclonal

Isotype

IgG

Research areas

Cancer >> Oncoproteins/suppressors >> Oncoproteins >> Signal transducers
Cancer >> Signal transduction >> Other
Cancer >> Cell cycle >> Kinases/phosphatases >> Other
Signal Transduction >> Protein Phosphorylation >> Tyrosine Kinases >> Receptor Tyrosine Kinases
Tags & Cell Markers >> Cell Type Markers >> Tumor Associated
Cell Biology >> Cell Cycle >> Kinases/Phosphatases >> Other

Applications

Show applications key

Our Abpromise guarantee covers the use of ab32828 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Function

May function as a signal transducer between specific cell types of mesodermal origin. In case of filovirus infection, seems to function as a cell entry factor.

Tissue specificity

Highly expressed in metastatic colon tumors. Expressed in primary colon tumors. Weakly expressed in normal colon tissue.

Sequence similarities

Belongs to the protein kinase superfamily. Tyr protein kinase family. AXL/UFO subfamily.
Contains 2 fibronectin type-III domains.
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 protein kinase domain.

Cellular localization

Membrane.

Target information above from: UniProt accessionP30530 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • Adhesion related kinase antibody
  • AI323647 antibody
  • Ark antibody
  • Axl antibody
  • AXL oncogene antibody
  • AXL receptor tyrosine kinase antibody
  • AXL transforming gene antibody
  • AXL transforming sequence/gene antibody
  • EC 2.7.10.1 antibody
  • JTK11 antibody
  • Oncogene AXL antibody
  • Tyro7 antibody
  • Tyrosine protein kinase receptor UFO antibody
  • Tyrosine-protein kinase receptor UFO antibody
  • UFO antibody
  • UFO_HUMAN antibody
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Database links

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References for Anti-Axl antibody (ab32828)

ab32828 has not yet been referenced specifically in any publications.

Publishing research using ab32828? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"