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Anti-Axl antibody (ab37861)

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Overview

Product name

Anti-Axl antibody
See all Axl products (8) ...

Description

Rabbit polyclonal to Axl

Tested applications

IHC-P, Flow Cyt, ELISA, WBmore details

Cross reactivity

Reacts with

Human

Immunogen

Synthetic peptide: RGTQAEESPFVGNPGNI conjugated to KLH, corresponding to N terminal amino acids 21-37 of Axl

RGTQAEESPF VGNPGNI

Positive control

SKBR3 cell lysate.

Properties

Form

Liquid

Storage instructions

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: 0.09% Sodium Azide
Constituents: PBS

Concentration

Concentration information loading...

Purity

Protein G purified

Clonality

Polyclonal

Isotype

IgG

  • Western blot - Axl antibody (ab37861)Western blot - Axl antibody (ab37861) image (enlarge)

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Axl antibody (ab37861)Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Axl antibody (ab37861) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab37861 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 1 Image

    IHC-P

     IHC-P: 1/50 - 1/100.

    IHC-P: 1/50 - 1/100.

  • Flow Cyt

     Flow Cyt: 1/10 - 1/50.

    Flow Cyt: 1/10 - 1/50.

  • ELISA

     ELISA: 1/1000

    ELISA: 1/1000

  • ShowHide1 Image

    WB

     WB: 1/100 - 1/500.Detect...Read more →

    WB: 1/100 - 1/500.Detects a band of approximately 97 kDa.

Target

Function

May function as a signal transducer between specific cell types of mesodermal origin. In case of filovirus infection, seems to function as a cell entry factor.

Tissue specificity

Highly expressed in metastatic colon tumors. Expressed in primary colon tumors. Weakly expressed in normal colon tissue.

Sequence similarities

Belongs to the protein kinase superfamily. Tyr protein kinase family. AXL/UFO subfamily.
Contains 2 fibronectin type-III domains.
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 protein kinase domain.

Cellular localization

Membrane.

Target information above from: UniProt accessionP30530 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • Adhesion related kinase antibody
  • AI323647 antibody
  • Ark antibody
  • Axl antibody
  • AXL oncogene antibody
  • AXL receptor tyrosine kinase antibody
  • AXL transforming gene antibody
  • AXL transforming sequence/gene antibody
  • EC 2.7.10.1 antibody
  • JTK11 antibody
  • Oncogene AXL antibody
  • Tyro7 antibody
  • Tyrosine protein kinase receptor UFO antibody
  • Tyrosine-protein kinase receptor UFO antibody
  • UFO antibody
  • UFO_HUMAN antibody
see all

Anti-Axl antibody images:

  Western blot - Axl antibody (ab37861)

Western blot - Axl antibody (ab37861)

Anti-Axl antibody (ab37861) at 1/1000 dilution + SKBR3 cell lysate

Secondary
HRP-anti-rabbit
developed using the ECL technique

Observed band size : 97 kDa (why is the actual band size different from the predicted?)
Additional bands at : 25 kDa. We are unsure as to the identity of these extra bands.

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Axl antibody (ab37861)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Axl antibody (ab37861)

ab37861 (1/50) staining human breast carcinoma tissue by immunohistochemistry, formalin-fixed, paraffin-embedded tissue.

References for Anti-Axl antibody (ab37861)

ab37861 has not yet been referenced specifically in any publications.

Publishing research using ab37861? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"