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Products:Cell Biology >> Cell Cycle >> Kinases/Phosphatases >> Other
Overview
Product name
Anti-Axl antibody
See all Axl products (8) ...
Description
Rabbit polyclonal to Axl
Tested applications
Cross reactivity
Reacts with
Mouse, Rat, Human
Predicted to work with
Pig, Xenopus laevis
Immunogen
A portion of amino acids 450-500 of human Axl (NP_068713.2).
Positive control
HUVEC cell lysate.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: 0.05% Sodium Azide
Constituents: 0.05% BSA, PBS
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Cancer >> Oncoproteins/suppressors >> Oncoproteins >> Signal transducers
Cancer >> Signal transduction >> Other
Cancer >> Cell cycle >> Kinases/phosphatases >> Other
Signal Transduction >> Protein Phosphorylation >> Tyrosine Kinases >> Receptor Tyrosine Kinases
Tags & Cell Markers >> Cell Type Markers >> Tumor Associated
Cell Biology >> Cell Cycle >> Kinases/Phosphatases >> Other
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Western blot - Axl antibody (ab72084)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab72084 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
WB
Application notes
WB: Use at a concentration of 0.5 - 1 µg/ml. Detects bands of approximately 20, 29 and 98 kDa (predicted molecular weight: 98 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
May function as a signal transducer between specific cell types of mesodermal origin. In case of filovirus infection, seems to function as a cell entry factor.
Tissue specificity
Highly expressed in metastatic colon tumors. Expressed in primary colon tumors. Weakly expressed in normal colon tissue.
Sequence similarities
Belongs to the protein kinase superfamily. Tyr protein kinase family. AXL/UFO subfamily.
Contains 2 fibronectin type-III domains.
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 protein kinase domain.
Cellular localization
Membrane.
Target information above from: UniProt accessionP30530
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- Adhesion related kinase antibody
- AI323647 antibody
- Ark antibody
see all
Database links
- Entrez Gene: 558 Human
- Entrez Gene: 26362 Mouse
- Entrez Gene: 100144875 Pig
- Entrez Gene: 308444 Rat
- Omim: 109135 Human
- SwissProt: P30530 Human
- SwissProt: Q00993 Mouse
- SwissProt: O55059 Rat
see all
Anti-Axl antibody images:
Western blot - Axl antibody (ab72084)
All lanes : Anti-Axl antibody (ab72084) at 0.5 µg/ml
Lane 1 : HUVEC cell lysate
Lane 2 : HUVEC cell lysate plus immunizing peptide
Predicted band size : 98 kDa
Observed band size : 98 kDa
Additional bands at : 20 kDa,29 kDa. We are unsure as to the identity of these extra bands.
References for Anti-Axl antibody (ab72084)
ab72084 has not yet been referenced specifically in any publications.
Publishing research using ab72084? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"