Anti-B MyB antibody (ab114055)

Overview

• Product nameAnti-B MyB antibodySee all B MyB primary antibodies ...
• Description
  Rabbit polyclonal to B MyB
• Tested applicationsIHC-P more details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Synthetic peptide, corresponding to a region between amino acids 450-500 of Human B MyB (NP_002457.1).

• Positive controlHuman Anaplastic Thyroid Carcinoma, Prostate Carcinoma and Testicular Seminoma tissues

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Storage bufferPreservative: 0.09% Sodium azide
  Constituents: 99% Tris buffered saline, 0.1% BSA
• Concentration information loading...
• PurityImmunogen affinity purified
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Cancer
  • Oncoproteins/suppressors
  • Oncoproteins
  • Transcription factors

  • Epigenetics and Nuclear Signaling
  • Transcription
  • Other factors

  • Epigenetics and Nuclear Signaling
  • Cell cycle
  • Cell Differentiation

  • Epigenetics and Nuclear Signaling
  • Transcription
  • Transcription Factors

  • Cell Biology
  • Cell Cycle
  • Cell differentiation

Applications

Target

• FunctionTranscription factor involved in the regulation of cell survival, proliferation, and differentiation. Transactivates the expression of the CLU gene.
• Sequence similaritiesContains 3 HTH myb-type DNA-binding domains.
• Post-translational
  modificationsPhosphorylated by cyclin A/CDK2 during S-phase. Phosphorylation at Thr-520 is probably involved in transcriptional activity.
• Cellular localizationNucleus.

Target information above from: UniProt accession P10244 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 4605 Human
  • Omim: 601415 Human
  • SwissProt: P10244 Human
  • Unigene: 179718 Human

• Alternative names
  B-Myb antibodyBMyB antibodyMGC15600 antibody

  MYB L2 antibodyMyb related protein B antibodyMyb-like protein 2 antibodyMyb-related protein B antibodyMybB antibodyMYBB_HUMAN antibodyMYBL 2 antibodyMybl2 antibodyv myb avian myeloblastosis viral oncogene homolog like 2 antibodyv myb myeloblastosis viral oncogene homolog (avian) like 2 antibodyv myb myeloblastosis viral oncogene homolog like 2 antibody

  see all

Anti-B MyB antibody images

• 

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-B MyB antibody (ab114055)
  ab114055, at 1/250 dilution, staining B MyB in formalin-fixed, paraffin-embedded Human prostate carcinoma tissue by Immunohistochemistry with DAB staining.