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Anti-B7 DC antibody [MIH14] (Phycoerythrin) (ab110184)

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Overview

  • Product nameAnti-B7 DC antibody [MIH14] (Phycoerythrin)See all B7 DC primary antibodies ...
  • Description
    Mouse monoclonal [MIH14] to B7 DC (Phycoerythrin)
  • ConjugationPhycoerythrin
  • Tested applicationsFlow Cyt more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Human B7-DC transfected L cells.

Properties

  • FormLiquid
  • Storage instructionsStore at +4°C in the dark. Do not freeze.
  • Storage bufferPreservative: 0.09% Sodium azide
    Constituents: 1% BSA, 5% Sucrose, PBS
  • Concentration information loading...
  • PurityProtein G purified
  • Purification notesPurified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
  • Clonality Monoclonal
  • Clone numberMIH14
  • MyelomaP3U1
  • IsotypeIgG1
  • Research Areas

Applications

Our Abpromise guarantee covers the use of ab110184 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
Flow Cyt Flow Cyt: 1/1. Use 10ul of the suggested working dilution to label 1x106 cells in 100ul

Target

  • FunctionInvolved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
  • Tissue specificityHighly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus.
  • Sequence similaritiesBelongs to the immunoglobulin superfamily. BTN/MOG family.
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Cellular localizationSecreted; Cell membrane and Endomembrane system.

    • Target information above from: UniProt accession Q9BQ51 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
    • Alternative names
        B7 dendritic cell molecule antibodyB7-DC antibodyB7DC antibody
        bA574F11.2 antibodyBtdc antibodyButyrophilin B7 DC antibodyButyrophilin B7-DC antibodyButyrophilin B7DC antibodyCD 273 antibodyCD273 antibodyCD273 antigen antibodyMGC142238 antibodyMGC142240 antibodyPD 1 ligand 2 antibodyPD L2 antibodyPD-1 ligand 2 antibodyPD-L2 antibodyPD1 ligand 2 antibodyPD1L2_HUMAN antibodyPDCD 1 ligand 2 antibodyPDCD1 ligand 2 antibodyPDCD1L2 antibodyPdcd1lg2 antibodyPDL 2 antibodyPDL2 antibodyProgrammed cell death 1 ligand 2 antibodyProgrammed death ligand 2 antibody
      see all

    Anti-B7 DC antibody [MIH14] (Phycoerythrin) images

    • Flow Cytometry - B7 DC antibody [MIH14] (Phycoerythrin) (ab110184)
      Flow Cytometry - B7 DC antibody [MIH14] (Phycoerythrin) (ab110184)
      ab110184 staining B7 DC in human peripheral blood monocytes by Flow cytometry.

    References for Anti-B7 DC antibody [MIH14] (Phycoerythrin) (ab110184)

    ab110184 has not yet been referenced specifically in any publications.

    Publishing research using ab110184 ? Please let us know so that we can cite the reference in this datasheet

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"