You have changed your country from  to  . Please be aware that this will change the currency in the purchasing process.

Overview

  • Product nameAnti-B7 DC antibody [TY25] (Phycoerythrin)See all B7 DC primary antibodies ...
  • Description
    Rat monoclonal [TY25] to B7 DC (Phycoerythrin)
  • ConjugationPhycoerythrin
  • Tested applicationsFlow Cyt more details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Mouse B7 DC transfected cell line.

  • Positive controlMouse splenocyte suspensions and B7 DC transfected cells

Properties

  • FormLiquid
  • Storage instructionsStore at +4°C in the dark. Do not freeze.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: PBS, 150mM Sodium chloride, pH 7.2
  • Concentration information loading...
  • PurityProtein G purified
  • Clonality Monoclonal
  • Clone numberTY25
  • IsotypeIgG2a
  • Light chain typekappa
  • Research Areas

Applications

Our Abpromise guarantee covers the use of ab93589 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
Flow Cyt
  • Application notesFlow Cyt: Use 0.06-0.5µg for 105-8 cells in 100ul.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Target

    • FunctionInvolved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
    • Tissue specificityHighly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus.
    • Sequence similaritiesBelongs to the immunoglobulin superfamily. BTN/MOG family.
      Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
      Contains 1 Ig-like V-type (immunoglobulin-like) domain.
    • Cellular localizationSecreted; Cell membrane and Endomembrane system.

      • Target information above from: UniProt accession Q9BQ51 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links
      • Alternative names
          B7 dendritic cell molecule antibodyB7-DC antibodyB7DC antibody
          bA574F11.2 antibodyBtdc antibodyButyrophilin B7 DC antibodyButyrophilin B7-DC antibodyButyrophilin B7DC antibodyCD 273 antibodyCD273 antibodyCD273 antigen antibodyMGC142238 antibodyMGC142240 antibodyPD 1 ligand 2 antibodyPD L2 antibodyPD-1 ligand 2 antibodyPD-L2 antibodyPD1 ligand 2 antibodyPD1L2_HUMAN antibodyPDCD 1 ligand 2 antibodyPDCD1 ligand 2 antibodyPDCD1L2 antibodyPdcd1lg2 antibodyPDL 2 antibodyPDL2 antibodyProgrammed cell death 1 ligand 2 antibodyProgrammed death ligand 2 antibody
        see all

      Anti-B7 DC antibody [TY25] (Phycoerythrin) images

      • Flow Cytometry - B7 DC antibody [TY25] (Phycoerythrin) (ab93589)
        Flow Cytometry - B7 DC antibody [TY25] (Phycoerythrin) (ab93589)
        Staining of non-transfected (left) and mouse B7 DC transfected (right) cells with 0.25µg PE Rat IgG2a isotype control (open histogram) or 0.06µg ab93589 (colored histogram). Total viable cells were used for analysis.

      References for Anti-B7 DC antibody [TY25] (Phycoerythrin) (ab93589)

      This product has been referenced in:
      • Tanaka K  et al. PDL1 is required for peripheral transplantation tolerance and protection from chronic allograft rejection. J Immunol 179:5204-10 (2007). Read more (PubMed: 17911605) »
      • Kanai T  et al. Blockade of B7-H1 suppresses the development of chronic intestinal inflammation. J Immunol 171:4156-63 (2003). Read more (PubMed: 14530338) »

      See all 4 Publications for this product

      Publishing research using ab93589 ? Please let us know so that we can cite the reference in this datasheet

      Product Wall

      Submit an Abreview for ab93589 Submit a Question for ab93589

      There are currently no Abreviews or Questions for ab93589.
      Please use the links above to contact us or submit feedback about this product.

      Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"