Loading...
You have changed your country from
to
. Please be aware that this will change the currency in the purchasing process.
Products:Cardiovascular >> Blood >> Other
Overview
Product name
Anti-BAALC antibody
See all BAALC products (3) ...
Description
Mouse polyclonal to BAALC
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Full length human BAALC protein (NP_079088.1, 145 a.a)
Positive control
BAALC transfected 293T cell lysate.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: 1X PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Neuroscience >> Neurology process >> Neural Signal Transduction
Cardiovascular >> Blood >> Other
-
Western blot - BAALC antibody (ab69043)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab69043 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/500 - 1/1000.Detects a band of approximately 18 kDa (predicted molecular weight: 16 kDa).
Target
Function
May play a synaptic role at the postsynaptic lipid rafts by interacting with CAMK2A.
Tissue specificity
Expressed by neural and hematopoietic cells. Expression is found both in normal early progenitor cells and in the most immature type of blasts in acute leukemia but not in mature hematopoietic cells. Isoform 2 and isoform 6 are expressed in the brain. Isoform 2 shows a low expression in neuroectoderm-derived tissues such as adrenal gland and no expression in bone marrow, peripheral blood lymphocytes or lymph nodes, or in tumors or cancer cell lines of nonneural tissue origin.
Post-translational
modifications
Palmitoylation and myristoylation target the protein to the lipid rafts.
Cellular localization
Cytoplasm. Membrane. Postsynaptic lipid rafts.
Target information above from: UniProt accessionQ8WXS3
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- BAALC antibody
- BAALC_HUMAN antibody
- Brain and acute leukemia cytoplasmic antibody
see all
Database links
- Entrez Gene: 79870 Human
- Omim: 606602 Human
- SwissProt: Q8WXS3 Human
- Unigene: 533446 Human
Anti-BAALC antibody images:
Western blot - BAALC antibody (ab69043)
All lanes : Anti-BAALC antibody (ab69043) at 1/500 dilution
Lane 1 : BAALC transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 25 µg per lane.
Secondary
Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution
Predicted band size : 16 kDa
Observed band size : 18 kDa (why is the actual band size different from the predicted?)
References for Anti-BAALC antibody (ab69043)
ab69043 has not yet been referenced specifically in any publications.
Publishing research using ab69043? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"