|
|
|
|
Western blot - BAAT antibody (ab54812)

(enlarge)
|
|
|
|
|
Product Name
|
BAAT antibody
|
| |
See all BAAT antibodies (2)...
|
|
Product type
|
Primary antibodies
|
|
Description
|
Mouse monoclonal to BAAT
|
|
Immunogen
|
Recombinant fragment: NGTNFPFGIP QVYHGQIHQP LPHSAQLIST NALGLLELYR TFETTQVGAS QYLFPIEEAQ GQFLFIVGEG DKTINSKAHA EQAIGQLKRH GKNNWTLL, corresponding to amino acids 258-356 of Human BAAT BLAST 'NGTNFPFGIP QVYHGQIHQP LPHSAQLIST NALGLLELYR TFETTQVGAS QYLFPIEEAQ GQFLFIVGEG DKTINSKAHA EQAIGQLKRH ' with or 
|
|
Reacts with
(species key)
|
Hu
|
|
Tested applications
(see key)
|
WB
|
|
|
Abreviews
|
|
|
|
Application notes
(see key)
|
Recommended dilutions WB: Use at a concentration of 1-5 µg/ml.
Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
|
|
Cellular localization
|
Cytoplasmic
|
|
Research areas
|
Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Metabolism of lipids and lipoproteins Signal Transduction >> Metabolism >> Lipid metabolism
|
|
Relevance
|
BAAT (bile acid Coenzyme A: amino acid N-acyltransferase) is involved in bile acid metabolism. In liver hepatocytes BAAT catalyzes the transfer of the bile acid moiety from the acyl-CoA thioester to glycine and taurine, before excretion into bile canaliculi. This is the second step in the formation of bile acid-amino acid conjugates. The conjugation increases the detergent properties of bile acids in the intestine, which facilitates lipid and fat-soluble vitamin absorption. BAAT may also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids.
|
|
|
|
|
Database links
|
The links below go to external sites and will open in a new browser window
|
|
Raised in
|
Mouse
|
|
Clonality
|
Monoclonal
|
|
Isotype
|
IgG1
|
|
Light chain type
|
kappa
|
|
Purity
|
Protein G purified
|
|
Storage buffer
|
Preservative: None PBS, pH 7.2
|
|
Form
|
Liquid
|
|
Concentration
|
1.000 mg/ml
|
|
Storage instructions
|
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
|
| |
At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this BAAT antibody is on this datasheet. But please do contact us if you would like any reassurance! |
 |
|
| |
BAAT antibody images:
|
Western blot - BAAT antibody (ab54812)
Predicted band size : 46 kDa
BAAT antibody (ab54812) at 1ug/lane + HepG2 cell lysate at 25ug/lane.
|
| |
| |
|
Search PubMed (MEDLINE) for references to BAAT
|
| |
BAAT antibody - more information
|
Customer reviews (feedback) regarding BAAT antibody |
Customer FAQs regarding BAAT antibody |
Protocols for BAAT antibody |
Price and availability of products related to BAAT antibody |
| |
BAAT antibody - other tools:
|
Contact Abcam with a Technical Enquiry about BAAT antibody |
| |
All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"