Anti-BACE1 antibody (ab2077)

ab2077 has been referenced in 14 publications.

1. Ding Y et al. Biochemical Inhibition of the Acetyltransferases ATase1 and ATase2 Reduces ß-Secretase (BACE1) Levels and Aß Generation. J Biol Chem 287:8424-33 (2012). WB. PubMed: 22267734
2. Zhao Y et al. Docosahexaenoic acid-derived neuroprotectin D1 induces neuronal survival via secretase- and PPAR?-mediated mechanisms in Alzheimer's disease models. PLoS One 6:e15816 (2011). WB; Mouse. PubMed: 21246057
3. Chakraborty R et al. Characterization of a Drosophila Alzheimer's disease model: pharmacological rescue of cognitive defects. PLoS One 6:e20799 (2011). WB; Human, Fruit fly (Drosophila melanogaster). PubMed: 21673973
4. Wozniak MA et al. Antivirals reduce the formation of key Alzheimer's disease molecules in cell cultures acutely infected with herpes simplex virus type 1. PLoS One 6:e25152 (2011). ICC; African Green Monkey. PubMed: 22003387
5. Jonas MC et al. AT-1 is the ER membrane acetyl-CoA transporter and is essential for cell viability. J Cell Sci 123:3378-88 (2010). WB; Chinese Hamster. PubMed: 20826464
6. Ko MH & Puglielli L Two endoplasmic reticulum (ER)/ER Golgi intermediate compartment-based lysine acetyltransferases post-translationally regulate BACE1 levels. J Biol Chem 284:2482-92 (2009). WB. PubMed: 19011241
7. Kitazume S et al. Molecular insights into beta-galactoside alpha2,6-sialyltransferase secretion in vivo. Glycobiology 19:479-87 (2009). WB; Human. PubMed: 19150807
8. Porayette P et al. Differential processing of amyloid-beta precursor protein directs human embryonic stem cell proliferation and differentiation into neuronal precursor cells. J Biol Chem 284:23806-17 (2009). WB; Human. PubMed: 19542221
9. Dong Y et al. The common inhalational anesthetic sevoflurane induces apoptosis and increases beta-amyloid protein levels. Arch Neurol 66:620-31 (2009). PubMed: 19433662
10. Zhang B et al. The Inhalation Anesthetic Desflurane Induces Caspase Activation and Increases Amyloid {beta}-Protein Levels under Hypoxic Conditions. J Biol Chem 283:11866-75 (2008). WB; Human. PubMed: 18326038
11. Woodard-Grice AV et al. Proteolytic shedding of ST6Gal-I by BACE1 regulates the glycosylation and function of alpha4beta1 integrins. J Biol Chem 283:26364-73 (2008). WB; Human. PubMed: 18650447
12. Xie Z et al. RNA interference silencing of the adaptor molecules ShcC and Fe65 differentially affect amyloid precursor protein processing and Abeta generation. J Biol Chem 282:4318-25 (2007). PubMed: 17170108
13. Xie Z et al. The inhalation anesthetic isoflurane induces a vicious cycle of apoptosis and amyloid beta-protein accumulation. J Neurosci 27:1247-54 (2007). WB; Human. PubMed: 17287498
14. Costantini C et al. An aging pathway controls the TrkA to p75NTR receptor switch and amyloid beta-peptide generation. EMBO J 25:1997-2006 (2006). PubMed: 16619032