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Product Name
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BACH1/BRIP1 antibody [3G11]
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See all BACH1/BRIP1 antibodies (6)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [3G11] to BACH1/BRIP1
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Immunogen
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Recombinant fusion protein (C-terminus of Human BACH1).
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Reacts with
(species key)
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Hu
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Tested applications
(see key)
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WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
WB: Use at a concentration of 1 - 3 µg/ml. Predicted molecular weight: 82 kDa.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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MCF7, HeLa, 293 and U2OS cell lysates.
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Cellular localization
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Nuclear
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Research areas
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Chromatin and Nuclear Signaling >> DNA / RNA >> DNA Damage & Repair >> DNA Damage Response >> BRCT Domain Proteins
Chromatin and Nuclear Signaling >> DNA / RNA >> DNA Damage & Repair >> Fanconi's Anemia
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Relevance
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BACH1 is a member of the DEAH helicase family that interacts with BRCA1, in vivo. The BACH1/BRCA1 complex formation contributes to a key function of BRCA1. Therefore, it is likely that BACH1 is a target of germline cancer-inducing mutations.
This Bach1/Brip1 protein should not be confused with the separate Bach1 protein listed under SwissProt O14867. This other protein is a BTB and CNC homolog 1 transcription factor.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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3G11
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Isotype
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IgG1
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Purity
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Protein A purified
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Storage buffer
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Preservative: 0.1% Sodium Azide
Constituents: PBS, pH 7.2 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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0.500 mg/ml
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Storage instructions
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Add glycerol to a final volume of 50%, aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this BACH1/BRIP1 antibody [3G11] is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to BACH1/BRIP1
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BACH1/BRIP1 antibody [3G11] - more information
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