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Western blot - BACH1 antibody (ab16608)
(enlarge)
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Product Name
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BACH1/BRIP1 antibody
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See all BACH1/BRIP1 antibodies (6)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to BACH1/BRIP1
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Immunogen
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Synthetic peptide within the extreme C-terminus of the human BACH1 protein sequence.
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Reacts with
(species key)
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Hu
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Tested applications
(see key)
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IP, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
IP: Use 2-4ul per IP.
WB: 1/2000 - 1/3000. Detects a band of approximately 130 kDa.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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HeLa whole cell extract, 293, MCF7 and SKOV3 whole cell extracts.
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Cellular localization
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Nuclear
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Research areas
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Chromatin and Nuclear Signaling >> DNA / RNA >> DNA Damage & Repair >> DNA Damage Response >> BRCT Domain Proteins
Chromatin and Nuclear Signaling >> DNA / RNA >> DNA Damage & Repair >> Fanconi's Anemia
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Relevance
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BACH1 is a member of the DEAH helicase family that interacts with BRCA1, in vivo. The BACH1/BRCA1 complex formation contributes to a key function of BRCA1. Therefore, it is likely that BACH1 is a target of germline cancer-inducing mutations.
This Bach1/Brip1 protein should not be confused with the separate Bach1 protein listed under SwissProt O14867. This other protein is a BTB and CNC homolog 1 transcription factor.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Whole antiserum
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Storage buffer
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Preservative: 0.01% Sodium Azide
Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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Concentration not determined - why is this?
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Storage instructions
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Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this BACH1/BRIP1 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for BACH1/BRIP1 antibody images, references, products related to ab16608 and other tools.
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BACH1/BRIP1 antibody images:
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 Western blot - BACH1 antibody (ab16608)
All lanes : BACH1/BRIP1 antibody (ab16608)
Lane 1 : MCF7
Lane 2 : HeLa
Lane 3 : 293
Lane 4 : SKOV3
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References for BACH1/BRIP1 antibody (ab16608)
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This product has been used in:
B tous R et al. Role of TLS DNA polymerases eta and kappa in processing naturally occurring structured DNA in human cells. Mol Carcinog 48:369-78 (2009). PubMed: 19117014
If you publish research using ab16608 please let us know so that we can cite the reference on this datasheet.
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Search PubMed (MEDLINE) for references to BACH1/BRIP1
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BACH1/BRIP1 antibody - more information
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Customer reviews (feedback) regarding BACH1/BRIP1 antibody |
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BACH1/BRIP1 antibody - related products:
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BACH1/BRIP1 antibody - other tools:
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Contact Abcam with a Technical Enquiry about BACH1/BRIP1 antibody |
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