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Western blot - BACH1 antibody (ab7288)

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Product Name
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BACH1/BRIP1 antibody
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See all BACH1/BRIP1 antibodies (6)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to BACH1/BRIP1
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Immunogen
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Synthetic peptide, corresponding to amino acids 1233-1249 of Human BACH1.
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Reacts with
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Hu
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Tested applications
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WB
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Abreviews
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Application notes
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Recommended dilutions WB: 1/500 - 1/1000. Detects a band of approximately 130 kDa (predicted molecular weight: 140 kDa).
Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Nuclear
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Research areas
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Chromatin and Nuclear Signaling >> DNA / RNA >> DNA Damage & Repair >> DNA Damage Response >> BRCT Domain Proteins Chromatin and Nuclear Signaling >> DNA / RNA >> DNA Damage & Repair >> Fanconi's Anemia
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Relevance
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BACH1 is a member of the DEAH helicase family that interacts with BRCA1, in vivo. The BACH1/BRCA1 complex formation contributes to a key function of BRCA1. Therefore, it is likely that BACH1 is a target of germline cancer-inducing mutations.
This Bach1/Brip1 protein should not be confused with the separate Bach1 protein listed under SwissProt O14867. This other protein is a BTB and CNC homolog 1 transcription factor.
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Database links
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The links below go to external sites and will open in a new browser window
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: 0.02% Sodium Azide Constituents: PBS Material safety datasheet (MSDS) for this product: Sodium Azide MSDS
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this BACH1/BRIP1 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for BACH1/BRIP1 antibody images, references, products related to ab7288 and other tools.
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BACH1/BRIP1 antibody images:
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Western blot - BACH1 antibody (ab7288)
All lanes : BACH1/BRIP1 antibody (ab7288) at 1/1000 dilution
Lane 1 : recombinant FLAG-tagged human BACH1 Lane 2 : IMR90 cell lysate Lane 3 : 293 cell lysate Lane 4 : MC7 cell lysate
Predicted band size : 140 kDa
Exposure time : 5 seconds This was submitted as part of a review by Dr Ron Drapkin
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Search PubMed (MEDLINE) for references to BACH1/BRIP1
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BACH1/BRIP1 antibody - more information
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Customer reviews (feedback) regarding BACH1/BRIP1 antibody |
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BACH1/BRIP1 antibody - related products:
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BACH1/BRIP1 antibody - other tools:
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Contact Abcam with a Technical Enquiry about BACH1/BRIP1 antibody |
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