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Western blot - BAG2 antibody (ab56741)
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Product Name
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BAG2 antibody
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See all BAG2 antibodies (6)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal to BAG2
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Immunogen
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Recombinant fragment, corresponding to amino acids 102-212 of Human BAG2
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Reacts with
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Hu
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Tested applications
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WB
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Abreviews
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Application notes
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Recommended dilutions
WB: Use at a concentration of 1-5 µg/ml.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Research areas
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Cancer >> Invasion/microenvironment >> Apoptosis >> Bcl 2 family
Signal Transduction >> Protein Trafficking >> Chaperones >> Other Chaperones
Cell Biology >> Apoptosis >> Intracellular >> Bcl2 Family
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Relevance
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BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Isotype
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IgG1
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Light chain type
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kappa
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Purity
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Protein G purified
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Storage buffer
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Preservative: None
PBS, pH 7.2
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this BAG2 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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BAG2 antibody images:
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 Western blot - BAG2 antibody (ab56741)
Predicted band size : 24 kDa
BAG2 antibody (ab56741) at 1ug/lane + HeLa cell lysate at 25ug/lane.
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Search PubMed (MEDLINE) for references to BAG2
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BAG2 antibody - more information
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Customer reviews (feedback) regarding BAG2 antibody |
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