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Products:Cell Biology >> Apoptosis >> Intracellular >> Bcl2 Family
Overview
Product name
Anti-BAG2 antibody
See all BAG2 products (7) ...
Description
Rabbit polyclonal to BAG2
Tested applications
WB, IHC-Pmore details
Cross reactivity
Reacts with
Mouse, Human
Predicted to work with
Rat, Chicken, Cow, Dog, Zebrafish
Immunogen
A region within synthetic peptide: EVPHGPVDQK FQSIVIGCAL EDQKKIKRRL ETLLRNIENS DKAIKLLEHS, corresponding to amino acids 145-194 of Human BAG2
EVPHGPVDQK FQSIVIGCAL EDQKKIKRRL ETLLRNIENS DKAIKLLEHS
Positive control
WB: Jurkat cell lysate. IHC-P: Human kidney tissue.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: 2% Sucrose, PBS
Concentration
Concentration information loading...
Purity
Protein A purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Cancer >> Invasion/microenvironment >> Apoptosis >> Bcl 2 family
Signal Transduction >> Protein Trafficking >> Chaperones >> Other Chaperones
Cell Biology >> Apoptosis >> Intracellular >> Bcl2 Family
Applications
Show applications key
Our Abpromise guarantee covers the use of ab58682 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use a concentration of 1.25 µg/mlDetects a band of approximately 23 kDa (predicted molecular weight: 24 kDa).
IHC-P: Use a concentration of 4 - 8 µg/ml.
Target
Function
Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release.
Sequence similarities
Contains 1 BAG domain.
Target information above from: UniProt accessionO95816
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- BAG 2 antibody
- BAG family molecular chaperone regulator 2 antibody
- BAG-2 antibody
see all
Database links
- Entrez Gene: 421880 Chicken
- Entrez Gene: 9532 Human
- Entrez Gene: 213539 Mouse
- Entrez Gene: 690038 Rat
- Entrez Gene: 393975 Zebrafish
- Omim: 603882 Human
- SwissProt: O95816 Human
- SwissProt: Q91YN9 Mouse
see all
Anti-BAG2 antibody images:
Western blot - BAG2 antibody (ab58682)
Anti-BAG2 antibody (ab58682) at 1.25 µg/ml + Jurkat cell lysate at 10 µg
Secondary
HRP conjugated anti Rabbit IgG at 1/50,000
Predicted band size : 24 kDa
Observed band size : 24 kDa
Immunohistochemistry (Paraffin-embedded sections) - BAG2 antibody (ab58682)
Ab58682 (4µg/ml) staining BAG2 in paraffin embedded human kidney tissue by immunohistochemistry. Epithelial cells of the renal tubule (indicated with arrows) were positively labelled. Magnification: x400
References for Anti-BAG2 antibody (ab58682)
This product has been referenced in:
- Carrettiero DCet al. The cochaperone BAG2 sweeps paired helical filament- insoluble tau from the microtubule. J Neurosci 29:2151-61 (2009). Mouse.Read more (PubMed: 19228967) »
See 1 publication for this product
Publishing research using ab58682? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"