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Western blot - BAI1 associated protein 2 isoform 3 antibody (ab791)
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Product Name
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BAI1 associated protein 2 isoform 3 antibody
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Product type
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Primary antibodies
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Description
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Goat polyclonal to BAI1 associated protein 2 isoform 3
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Immunogen
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Synthetic peptide: SMSSADVEVARF, corresponding to C terminal amino acids 509-520 of Human BAI1 associated protein 2 isoform 3.
BLAST 'C-SMSSADVEVARF' with  or 
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Reacts with
(species key)
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Hu
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Specificity
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This antibody will only recognise isoform 3 of the three reported isoforms.
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Tested applications
(see key)
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WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
Western Blot – Approx 50kDa band seen in HeLa cell lysates.
Recommended for use at 2-5µg/ml.
Overnight incubation is recommended with this antibody
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Positive control
(see definition)
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HeLa cell lysates
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Cellular localization
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Cell Membrane and Cytoplasmic
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Research areas
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Neuroscience >> Cell Type Marker >> Neuron marker >> Growth Cone
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Relevance
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BAIAP2, a target of p53, has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This interaction at the cytoplasmic membrane is crucial to the function of this protein, which may be involved in neuronal growth-cone guidance. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis.
Brain-specific angiogenesis inhibitor (BAI1)-binding protein may be involved in neuronal growth-cone guidance.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Goat
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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IgG fraction
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Storage buffer
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Tris saline, 0.02% Na azide, pH7.3 with 0.5% BSA Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Purification notes
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Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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Form
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Liquid
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Concentration
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0.500 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this BAI1 associated protein 2 isoform 3 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for BAI1 associated protein 2 isoform 3 antibody images, references, products related to ab791 and other tools.
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BAI1 associated protein 2 isoform 3 antibody images:
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 Western blot - BAI1 associated protein 2 isoform 3 antibody (ab791)
ab791 staining (1µg/ml) of Human Brain (Cerebellum) lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 12 hour. Detected by western blot using chemiluminescence.
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Search PubMed (MEDLINE) for references to BAI1 associated protein 2 isoform 3
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BAI1 associated protein 2 isoform 3 antibody - more information
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BAI1 associated protein 2 isoform 3 antibody - related products:
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