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Products:Neuroscience >> Cell Type Marker >> Neuron marker >> Growth Cone
Overview
Product name
Anti-BAI1 associated protein 2 isoform 3 antibody
Description
Goat polyclonal to BAI1 associated protein 2 isoform 3
Specificity
This antibody will only recognise isoform 3 of the three reported isoforms.
Tested applications
Cross reactivity
Reacts with
Human
Predicted to work with
Cow, Dog
Immunogen
Synthetic peptide: SMSSADVEVARF, corresponding to C terminal amino acids 509-520 of Human BAI1 associated protein 2 isoform 3.
C-SMSSADVE VARF
Positive control
HeLa cell lysates
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
Concentration
Concentration information loading...
Purity
IgG fraction
Purification notes
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Primary antibody notes
Brain-specific angiogenesis inhibitor (BAI1)-binding protein may be involved in neuronal growth-cone guidance.
Clonality
Polyclonal
Isotype
IgG
Research areas
Neuroscience >> Cell Type Marker >> Neuron marker >> Growth Cone
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Western blot - BAI1 associated protein 2 isoform 3 antibody (ab791)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab791 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use a concentration of 1 - 3 µg/ml.
Target
Relevance
BAIAP2, a target of p53, has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This interaction at the cytoplasmic membrane is crucial to the function of this protein, which may be involved in neuronal growth-cone guidance. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis.
Cellular localization
Cell Membrane and Cytoplasmic
Alternative names
- BAI associated protein 2 antibody
- BAIAP2 antibody
- BAP2 antibody
see all
Database links
- Entrez Gene: 10458 Human
- Omim: 605475 Human
- SwissProt: Q9UQB8 Human
- Unigene: 128316 Human
Anti-BAI1 associated protein 2 isoform 3 antibody images:
Western blot - BAI1 associated protein 2 isoform 3 antibody (ab791)
ab791 staining (1µg/ml) of Human Brain (Cerebellum) lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 12 hour. Detected by western blot using chemiluminescence.
References for Anti-BAI1 associated protein 2 isoform 3 antibody (ab791)
ab791 has not yet been referenced specifically in any publications.
Publishing research using ab791? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"